PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 14597759-6 2003 In response to intraperitoneal thioglycollate, recruitment of leukocytes in OPN-/- mice was impaired, and OPN-/- leukocytes exhibited decreased basal and MCP-1-directed migration. Thioglycolates 31-45 secreted phosphoprotein 1 Mus musculus 76-79 23192608-10 2013 We generated chimeric mice expressing mutated forms of OPN in myeloid-derived leukocytes, and found that the SLAYGLR functional domain of OPN, but not the RGD, mediates macrophage accumulation in response to thioglycollate-elicited peritonitis. Thioglycolates 208-222 secreted phosphoprotein 1 Mus musculus 138-141 8881770-4 1996 This report documents (1) that thioglycollate-elicited peritoneal macrophages, activated with the inflammatory mediators, produced less NO and exhibited reduced cytotoxicity towards target cells when they were obtained from old animals than when they were obtained from young animals; and (2) that OPN was able to inhibit both the induced NO synthesis and cytotoxicity, but more effectively in macrophages from the young animals than those from the old animals. Thioglycolates 31-45 secreted phosphoprotein 1 Mus musculus 298-301