PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10770802-3 2000 The TCR energy maps for QL9/L(d) and SIYR/K(b) were remarkably similar, in that 16 of 41 Valpha and Vbeta alanine mutants showed reduced binding to both ligands. valpha 89-95 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 4-7 9730891-3 1998 By fixing TCR-beta chains with a single rearranged TCR-beta irrelevant to the selecting ligand, we show here that T cells selected to mature on a single MHC-peptide complex express highly restricted TCR-alpha chains in terms of Valpha usage and amino acid residue of their CDR3 loops, whereas such restriction was not observed with those selected by the same MHC with diverse sets of self-peptides including this peptide. valpha 228-234 T cell receptor beta variable 20/OR9-2 (non-functional) Homo sapiens 10-18