PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 19202742-1 2008 Some acetophenone (CAS 98-86-2) derived bis Mannich bases, bis-(3-aryl-3-oxo-propyl)-methylamine hydrochlorides (B1-B5) and representative piperidinols, 4-aryl-3-arylcarbonyl-1-methyl-4-piperidinol hydrochlorides (C1, C2 and C5), which are the structural isomers of B1, B2 and B5, were synthesized and their effects on DNA topoisomerase I were tested. acetophenone 5-17 immunoglobulin kappa variable 7-3 (pseudogene) Homo sapiens 266-279 12572525-1 2002 Some acetophenone derived bis Mannich bases (B1-B5) and piperidinols (C1, C4), which are the structural isomers of B1 and B4, and also quaternary piperidine derivative C6 were synthesized and studied for anticonvulsant activity. acetophenone 5-17 immunoglobulin kappa variable 7-3 (pseudogene) Homo sapiens 115-124