PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20352598-1	2010	Two strongly correlated polymorphisms located within the gene of the glucokinase regulator protein (GKRP), rs780094 and rs1260326, are associated with increased plasma triglyceride levels and provide a genetic model for the long-term activation of hepatic glucokinase.	Triglycerides	168-180	glucokinase	Homo sapiens	69-80	
28158221-9	2017	Multiple logistic regression analyses revealed that fasting glucose concentration in plasma and SNP rs2908289 in GCK were associated with microalbuminuria, and adjustment for age, gender, smoking history, systolic blood pressure, waist circumference, and serum triglyceride levels did not attenuate this association.	Triglycerides	261-273	glucokinase	Homo sapiens	113-116	
23139355-6	2013	Furthermore, despite elevated glucose concentrations, carriers of GCK mutations showed lower levels of free fatty acids and triglycerides than healthy control subjects.	Triglycerides	124-137	glucokinase	Homo sapiens	66-69	
21490074-7	2011	RESULTS: Hepatic GCK mRNA expression is associated with triglyceride content in human liver biopsies (r = 0.50, P = 0.0002).	Triglycerides	56-68	glucokinase	Homo sapiens	17-20	
21490074-10	2011	CONCLUSIONS: In this study, we demonstrate for the first time that GCK mRNA expression is associated with markers of de novo lipogenesis and liver triglyceride content in humans.	Triglycerides	147-159	glucokinase	Homo sapiens	67-70	
20352598-0	2010	Glucokinase-activating GCKR polymorphisms increase plasma levels of triglycerides and free fatty acids, but do not elevate cardiovascular risk in the Ludwigshafen Risk and Cardiovascular Health Study.	Triglycerides	68-81	glucokinase	Homo sapiens	0-11	
30245511-7	2019	In the newly diagnosed diabetic patients (New-DM), a triglyceride cutoff <=1.43 mmol/L (126.55 mg/dl) could discriminate GCK-DM from T2DM with 100% sensitivity and 68.4% specificity.	Triglycerides	53-65	glucokinase	Homo sapiens	124-127	
30245511-9	2019	A clinical criterion based on triglyceride and mild hyperglycemia could differentiate GCK-DM from T2DM in New-DM and was shown to be effective in identifying GCK-DM from 559 early-onset young patients with T2DM in the hospital.	Triglycerides	30-42	glucokinase	Homo sapiens	86-89	
30245511-9	2019	A clinical criterion based on triglyceride and mild hyperglycemia could differentiate GCK-DM from T2DM in New-DM and was shown to be effective in identifying GCK-DM from 559 early-onset young patients with T2DM in the hospital.	Triglycerides	30-42	glucokinase	Homo sapiens	158-161	
25692341-0	2015	Glucokinase regulatory protein: complexity at the crossroads of triglyceride and glucose metabolism.	Triglycerides	64-76	glucokinase	Homo sapiens	0-11	
24918535-11	2014	CONCLUSIONS: Individuals who are homozygous TT at rs1260326 of the GCKR gene have higher triglyceride, total and LDL cholesterol levels regardless of the presence of GCK mutations.	Triglycerides	89-101	glucokinase	Homo sapiens	67-70	
19073768-7	2009	RESULTS: The T-allele of GCKR rs780094 was associated with increased triglycerides (P = 5.4 x 10(-7)), while the A-allele of GCK rs1799884 was associated with higher FPG (P = 3.1 x 10(-7)).	Triglycerides	69-82	glucokinase	Homo sapiens	25-28	
19643913-0	2009	The P446L variant in GCKR associated with fasting plasma glucose and triglyceride levels exerts its effect through increased glucokinase activity in liver.	Triglycerides	69-81	glucokinase	Homo sapiens	125-136	
19643913-14	2009	Altered GCK regulation in liver is predicted to enhance glycolytic flux, promoting hepatic glucose metabolism and elevating concentrations of malonyl-CoA, a substrate for de novo lipogenesis, providing a mutational mechanism for the reported association of this variant with raised triglycerides and lower glucose levels.	Triglycerides	282-295	glucokinase	Homo sapiens	8-11	
34677673-7	2022	GCK variant carriers exhibited a significantly lower body mass index and serum triglyceride levels when compared to GCK variant non-carriers.	Triglycerides	79-91	glucokinase	Homo sapiens	0-3	
15788789-0	2005	Are glucokinase mutations associated with low triglycerides?	Triglycerides	46-59	glucokinase	Homo sapiens	4-15	
34634522-5	2021	RESULTS: We identified strong correlations between plasma triacylglycerols (TAGs) and islet gene modules that comprise key regulators of glucose- and lipid-regulated insulin secretion and of the insulin signaling pathway, the two top hits were Gck and Abhd6 for positive and negative correlations, respectively.	Triglycerides	58-74	glucokinase	Homo sapiens	244-247