PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28701570-10 2017 Using a logistic regression analysis and adjusting for age, BMI, hsCRP, non-HDLc, and triglycerides, FABP4 was independently associated with breast cancer (odds ratio [OR]: 1.091 [95% CI: 1.037-1.149]). Triglycerides 86-99 fatty acid binding protein 4 Homo sapiens 101-106 28847153-9 2018 Additionally, in multivariable linear regression analysis, FABP4 was linked to estimated glomerular filtration rate ( P < .001), gender ( P = .005), fasting triglycerides ( P = .048), and body mass index ( P < .001). Triglycerides 160-173 fatty acid binding protein 4 Homo sapiens 59-64 29316087-9 2018 In the control group, serum A-FABP was positively correlated only with TG, and uncorrelated with the other indices (P > 0.05). Triglycerides 71-73 fatty acid binding protein 4 Homo sapiens 28-34 31966732-11 2017 SBP and log-TG were independent predictors of the serum A-FABP level among KT patients. Triglycerides 12-14 fatty acid binding protein 4 Homo sapiens 56-62 26754658-8 2016 Change in FABP4 level by omega-3 fatty acids was negatively correlated with change in levels of EPA + DHA (r = -0.643, P = 0.013), EPA (r = -0.540, P = 0.046) and DHA (r = -0.650, P = 0.011) but not change in the level of triglycerides or other fatty acid composition. Triglycerides 222-235 fatty acid binding protein 4 Homo sapiens 10-15 24957697-7 2014 After adjusting for age and sex, we observed that body mass index (BMI), diastolic blood pressure, waist circumference, body fat percentage, triglycerides, and serum RBP4 levels were positively associated with serum A-FABP levels in all subjects. Triglycerides 141-154 fatty acid binding protein 4 Homo sapiens 216-222 25506691-9 2014 U-FABP4 level was positively correlated with age, systolic blood pressure and levels of serum FABP4 (S-FABP4), triglycerides, hemoglobin A1c (HbA1c), urinary FABP1 (U-FABP1) and UACR (r = 0.360, p<0.001). Triglycerides 111-124 fatty acid binding protein 4 Homo sapiens 2-7 27819006-6 2016 A-FABP was significantly correlated with glycated hemoglobin A1C (HbA1C), BMI, triglyceride, Homeostasis Model Assessment Index (HOMA-IR), waist hip rate, C-reactive protein, IL-6, and HDL-C in obese subjects with type 2 diabetes. Triglycerides 79-91 fatty acid binding protein 4 Homo sapiens 0-6 25096952-2 2014 We recently showed that FABP4 regulates triglyceride accumulation in primary human trophoblasts. Triglycerides 40-52 fatty acid binding protein 4 Homo sapiens 24-29 24150574-6 2014 RESULTS: Serum A-FABP positively correlated with body fat percentage, total cholesterol, serum triglycerides and erythrocyte sedimentation rate. Triglycerides 95-108 fatty acid binding protein 4 Homo sapiens 15-21 21720879-1 2011 Increased expression of adipocyte fatty acid binding protein (FABP4) is associated with type 2 diabetic, high triglycerides, increased lipid peroxidation, and inflammation markers. Triglycerides 110-123 fatty acid binding protein 4 Homo sapiens 62-67 23731091-7 2013 Similar results were also found in the expressions of enzymes involved in triglyceride and cholesterol biosyntheses including glycerol-3-phosphate acyltransferase (GPAT), 3-hydroxy-3-methyl-glutaryl CoA reductase (HMGCoR), adipocyte-specific fatty acid binding protein (A-FABP), and SREBP-2. Triglycerides 74-86 fatty acid binding protein 4 Homo sapiens 223-268 23731091-7 2013 Similar results were also found in the expressions of enzymes involved in triglyceride and cholesterol biosyntheses including glycerol-3-phosphate acyltransferase (GPAT), 3-hydroxy-3-methyl-glutaryl CoA reductase (HMGCoR), adipocyte-specific fatty acid binding protein (A-FABP), and SREBP-2. Triglycerides 74-86 fatty acid binding protein 4 Homo sapiens 270-276 22717543-8 2012 FABP4 level was positively correlated with age, body mass index (BMI), blood pressure, and triglycerides and negatively correlated with the M value. Triglycerides 91-104 fatty acid binding protein 4 Homo sapiens 0-5 21186114-7 2012 At the 4-year follow-up, subjects in the highest FABP4 tertile at baseline exhibited higher values for body mass index, fat mass and percent body fat, as well as blood pressure, fasting glucose, total cholesterol, triglycerides, low-density lipoprotein (LDL)-cholesterol, insulin, homeostasis model assessment of insulin resistance, monocyte chemoattractant protein-1 and tumor necrosis factor-alpha levels (all P<0.05). Triglycerides 214-227 fatty acid binding protein 4 Homo sapiens 49-54 22490689-8 2012 Additionally, after adjustment for body mass index and age, the serum A-FABP level showed significant positive correlations with TC, TG and LDL-C (r = 0.469, P = 0.000; r = 0.239, P = 0.035 and r = 0.366, P = 0.001). Triglycerides 133-135 fatty acid binding protein 4 Homo sapiens 70-76 24044564-5 2013 A-FABP was an independent predictor of triglyceride:high-density lipoprotein cholesterol, explaining 42% of its variation in overweight/obese women. Triglycerides 39-51 fatty acid binding protein 4 Homo sapiens 0-6 24044564-7 2013 A-FABP predicted atherogenic risk, with an odds ratio of 11.2 (95% CI: 3.7-34.2), 7.1 (1.9-27.2) and 6.7 (2.6-17.2) for having elevated triglyceride:high-density lipoprotein cholesterol, apoB and CRP, respectively, and IR with an odds ratio 5.6 (1.8-17.2). Triglycerides 136-148 fatty acid binding protein 4 Homo sapiens 0-6 21525163-13 2011 The reduced triglyceride content after FABP4 inhibition suggests that FABP4 is essential for trophoblast lipid accumulation. Triglycerides 12-24 fatty acid binding protein 4 Homo sapiens 39-44 21063874-5 2011 Serum A-FABP at baseline was significantly correlated with the body mass index (r = 0.45, P = 0.01), homeostasis model assessment as a marker of insulin resistance (r = 0.53, P < 0.01), and systolic blood pressure (r = 0.37, P = 0.047), and tended to be correlated with low-density lipoprotein cholesterol, triglyceride, and CAVI. Triglycerides 310-322 fatty acid binding protein 4 Homo sapiens 6-12 21251185-8 2011 FABP-4 concentration was positively correlated with body mass index (BMI), HOMA-IR, and the concentrations of insulin, total cholesterol, triglycerides, sTNF-R1, leptin and IL-18, but showed a negative correlation with high-density lipoprotein (HDL) cholesterol and adiponectin concentrations. Triglycerides 138-151 fatty acid binding protein 4 Homo sapiens 0-6 21525163-13 2011 The reduced triglyceride content after FABP4 inhibition suggests that FABP4 is essential for trophoblast lipid accumulation. Triglycerides 12-24 fatty acid binding protein 4 Homo sapiens 70-75 21336983-0 2011 Receptor mediated elevation in FABP4 levels by advanced glycation end products induces cholesterol and triacylglycerol accumulation in THP-1 macrophages. Triglycerides 103-118 fatty acid binding protein 4 Homo sapiens 31-36 22046439-6 2011 Serum levels of A-FABP were demonstrated to be positively correlated with gender and waist circumference both at baseline and the end of the study, and with age, body mass index (BMI), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and NT-proBNP at 48 weeks (all P<0.05). Triglycerides 209-221 fatty acid binding protein 4 Homo sapiens 16-22 22102888-8 2011 Multiple regression analysis indicated that HD duration, BMI, and triglycerides level were independent determinants for FABP4 level. Triglycerides 66-79 fatty acid binding protein 4 Homo sapiens 120-125 22102888-10 2011 Cox proportional hazard regression analysis showed that logarithmically transformed FABP4 level was an independent predictor of cardiovascular death adjusted for age, gender, HD duration, BMI, and triglycerides level (hazard ratio, 7.75; 95% CI, 1.05-25.31). Triglycerides 197-210 fatty acid binding protein 4 Homo sapiens 84-89 22046439-6 2011 Serum levels of A-FABP were demonstrated to be positively correlated with gender and waist circumference both at baseline and the end of the study, and with age, body mass index (BMI), total cholesterol (TC), triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and NT-proBNP at 48 weeks (all P<0.05). Triglycerides 223-225 fatty acid binding protein 4 Homo sapiens 16-22 20388924-6 2010 In FCHL, FABP4 correlated to body mass index (BMI), waist circumference, insulin levels, and homeostasis model assessment (HOMA) index (all P< 0.05), but not to lipid levels, whereas in obese patients, FABP4 correlated to triglyceride levels (r = 0.303, P= 0.014) and very low density lipoprotein size (r = 0.502, P = 0.001), as determined by nuclear magnetic resonance. Triglycerides 225-237 fatty acid binding protein 4 Homo sapiens 9-14 21167393-9 2010 TG, TCH, and waist circumference were independent predictors of serum FABP4 levels in HD patients. Triglycerides 0-2 fatty acid binding protein 4 Homo sapiens 70-75 20009357-6 2010 Multivariate forward stepwise linear regression analysis of the significant variables showed that the level of triglycerides (beta=0.348, R(2)=0.121, P<0.001) was the independent predictor of fasting serum level of FABP4. Triglycerides 111-124 fatty acid binding protein 4 Homo sapiens 218-223 18710473-7 2009 Circulating A-FABP levels were significantly associated with body mass index (BMI), waist circumference, triglyceride, alanine aminotransferase (ALT), lipocalin-2 and high-sensitivity C-reactive protein (hsCRP) levels. Triglycerides 105-117 fatty acid binding protein 4 Homo sapiens 12-18 19368945-7 2009 Subjects within the highest quartile of A-FABP levels had correspondingly poor metabolic risk profiles (BMI, waist circumference, triglycerides, high-density lipoprotein cholesterol, fasting insulin, and homeostasis model assessment of insulin resistance) compared with those in the lowest A-FABP quartile (P < .01). Triglycerides 130-143 fatty acid binding protein 4 Homo sapiens 40-46 20533865-6 2010 In a combined population of all groups, serum FABP-4 levels correlated positively with BMI, body fat content, serum glucose, triglycerides, HbA1c and HOMA index and were inversely related to HDL-cholesterol, resting energy expenditure and freeT3 levels. Triglycerides 125-138 fatty acid binding protein 4 Homo sapiens 46-52 18421072-5 2008 In type 2 diabetic subjects, FABP4 was positively correlated with plasma triglycerides (P = 0.007), apolipoprotein C-III (apoC-III) (P = 0.009), and all the components of triglyceride-rich lipoproteins, including VLDL triglycerides (P = 0.002), VLDL-cholesterol (P = 0.001), and VLDL apoB (P = 0.001). Triglycerides 73-86 fatty acid binding protein 4 Homo sapiens 29-34 18849305-6 2009 In addition, markers of adiposity (body mass index, serum leptin), triglycerides and serum creatinine were independently associated with circulating AFABP (P<0.05). Triglycerides 67-80 fatty acid binding protein 4 Homo sapiens 149-154 18835952-9 2009 Age- and sex-adjusted A-FABP showed positive correlations with BMI, waist-to-hip ratio, waist circumference, triglycerides, gamma-glutamyltransferase, fasting insulin, homeostasis model assessment of insulin resistance (HOMA-IR), A1C, and C-reactive protein (CRP) but showed negative correlation with HDL cholesterol. Triglycerides 109-122 fatty acid binding protein 4 Homo sapiens 22-28 18835952-11 2009 The OR in the highest tertile of A-FABP remained significant after adjustments for BMI, waist circumference, A1C, HDL cholesterol, triglycerides, HOMA-IR, CRP, and hepatic enzymes. Triglycerides 131-144 fatty acid binding protein 4 Homo sapiens 33-39 18835952-12 2009 CONCLUSIONS: Our study demonstrates that serum A-FABP is significantly associated with NAFLD in type 2 diabetes, independent of BMI, waist circumference, HOMA-IR, A1C, triglycerides, HDL cholesterol, and CRP. Triglycerides 168-181 fatty acid binding protein 4 Homo sapiens 47-53 18421072-5 2008 In type 2 diabetic subjects, FABP4 was positively correlated with plasma triglycerides (P = 0.007), apolipoprotein C-III (apoC-III) (P = 0.009), and all the components of triglyceride-rich lipoproteins, including VLDL triglycerides (P = 0.002), VLDL-cholesterol (P = 0.001), and VLDL apoB (P = 0.001). Triglycerides 218-231 fatty acid binding protein 4 Homo sapiens 29-34 17553506-4 2007 FABP4 levels in T2D subjects were positively correlated to the number of MS elements, obesity degree, adiponectin, triglycerides, lipoperoxides, C-reactive protein, age, systolic blood pressure and diabetes duration (p<0.05). Triglycerides 115-128 fatty acid binding protein 4 Homo sapiens 0-5 17983623-8 2008 Similarly, FABP4 concentration significantly increased with an increasing of MS features and was strongly correlated with body-mass index, triglycerides, HDL-cholesterol concentrations, insulin and blood pressure. Triglycerides 139-152 fatty acid binding protein 4 Homo sapiens 11-16 16313911-4 2006 Here, we showed that overexpression of the ALBP gene using a lentiviral construct in macrophage foam cells enhanced the accumulations of cholesterol and triglyceride, probably due to an increased expression of the scavenger receptor type AI (SR-AI), which plays an important role in cell lipid metabolism. Triglycerides 153-165 fatty acid binding protein 4 Homo sapiens 43-47 16313911-7 2006 These results have determined that ALBP gene expression accelerates cholesterol and triglyceride accumulation in macrophage foam cells and affects some key gene expression for lipid metabolism, suggesting some pivotal roles of ALBP in lipid metabolism for macrophage foam cell formation. Triglycerides 84-96 fatty acid binding protein 4 Homo sapiens 35-39 33901630-8 2021 Moreover, exogenous expression of FABP4 increased triglyceride levels and enhanced lipid accumulation caused by VPA. Triglycerides 50-62 fatty acid binding protein 4 Homo sapiens 34-39 15686734-8 2004 These data suggest that rapamycin-induced aP2 may play a role in increased triglyceride accumulation. Triglycerides 75-87 fatty acid binding protein 4 Homo sapiens 42-45 34839983-10 2022 In vitiligo patients, there were significant positive correlations between FABP4 serum levels and triglycerides (p = 0.047), cholesterol (p = 0.001) and LDL (p = 0.001) levels and negative correlation regarding HDL level (p = 0.009). Triglycerides 98-111 fatty acid binding protein 4 Homo sapiens 75-80 33840283-9 2021 CONCLUSION: FABP4 correlates with high DBP in the non-active and high triglyceride serum in the active episode. Triglycerides 70-82 fatty acid binding protein 4 Homo sapiens 12-17 33088219-5 2020 Meanwhile, the regulatory role of FABP4 in the energy and lipid metabolism was evaluated by the levels of triglyceride, ATP, LDH, glycerol and NEFA. Triglycerides 106-118 fatty acid binding protein 4 Homo sapiens 34-39 33151094-3 2020 Results: FABP4 level was elevated in RA patients and positively associated with 28-joint disease activity score, high-sensitivity C-reactive protein, erythrocyte sedimentation rate, total cholesterol, triglyceride and low-density lipoprotein cholesterol. Triglycerides 201-213 fatty acid binding protein 4 Homo sapiens 9-14 33143633-3 2020 RESULTS: U-FABP4 was negatively correlated with estimated glomerular filtration rate (eGFR) (r = - 0.56, P < 0.01) and was positively correlated with age, blood pressure, triglycerides, proteinuria (r = 0.58, P < 0.01), plasma FABP4 and urinary FABP1 (U-FABP1) (r = 0.52, P < 0.01). Triglycerides 171-184 fatty acid binding protein 4 Homo sapiens 11-16