PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 3924035-10 1985 Tyrosinase shows a tendency to aggregate, at low protein concentration, and a resistance to dissociation by urea or SDS so remarkable that gel-permeation chromatography in 4M-urea does not affect the equilibrium, and the band obtained on SDS/polyacrylamide-gel electrophoresis is a dimer. polyacrylamide 242-256 tyrosinase Mus musculus 0-10 2501395-5 1989 Sodium dodecyl sulfate polyacrylamide gel electrophoresis of tyrosinase in the large granule fraction shows that in analogy with electron microscopic observations, glutathione blocks the reappearance of membrane-bound T3 tyrosinase which occurs in the theophylline-treated control during the recovery process, whereas the dynamics of T1 tyrosinase is almost the same as that of the control. polyacrylamide 23-37 tyrosinase Mus musculus 61-71 3097004-10 1986 When digested with proteases and glycosidases, higher molecular weight forms of tyrosinase co-migrated with the purified enzyme in isoelectric focusing and sodium dodecyl sulfate-polyacrylamide gel electrophoresis suggesting that the isozyme was derived from larger precursors. polyacrylamide 179-193 tyrosinase Mus musculus 80-90 6826662-4 1983 Using two-dimensional polyacrylamide gel electrophoresis, we have identified four cellular proteins whose production is modulated during melanogenesis, a process which includes concomitant increases in levels of tyrosinase, the rate limiting enzyme for melanin biosynthesis, melanization, and ultimately, cell death. polyacrylamide 22-36 tyrosinase Mus musculus 212-222 806638-0 1975 Inability of murine melanoma melanosomal "tyrosinase" (L-dopa oxidase) to oxidize tyrosine to melanin in polyacrylamide gel systems. polyacrylamide 105-119 tyrosinase Mus musculus 41-52 806638-1 1975 Melanosomal "tyrosinase" (L-dopa) was isolated from trypsin digest of B-16 mouse melanoma melanosomes, using polyacrylamide gel disc electrophoresis. polyacrylamide 109-123 tyrosinase Mus musculus 12-23