PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27249651-8	2016	This result indicated that thalidomide regulated angiogenesis via the inhibition of HIF-1alpha and HIF-2alpha expression, which further regulated downstream factors, including VEGF, NOTCH1, DLL4, and Ang2.	Thalidomide	27-38	delta like canonical Notch ligand 4	Homo sapiens	190-194	
24219762-0	2014	Thalidomide-induced angiopoietin 2, Notch1 and Dll4 downregulation under hypoxic condition in tissues with gastrointestinal vascular malformation and human umbilical vein endothelial cells.	Thalidomide	0-11	delta like canonical Notch ligand 4	Homo sapiens	47-51	
24219762-4	2014	In addition, in vitro effect of thalidomide on Ang2, Notch1 and Dll4 in human umbilical vein endothelial cells (HUVEC) and on HUVEC proliferation was also investigated during normoxic and hypoxic conditions.	Thalidomide	32-43	delta like canonical Notch ligand 4	Homo sapiens	64-68	
24219762-9	2014	CONCLUSION: Ang2, Notch1, Dll4 and Hif-1alpha may play an important role in the pathogenesis of GIVM and may be potential targets of thalidomide in the treatment of the disease.	Thalidomide	133-144	delta like canonical Notch ligand 4	Homo sapiens	26-30	
22883339-8	2012	CONCLUSION: Ang2, Notch1 and Dll4 may correlate with the pathogenesis of GIVM, while thalidomide can concentration-dependently down-regulate the expression of Ang2, Notch1 and Dll4, which may be one of the mechanism that thalidomide play a therapeutic role in GIVM.	Thalidomide	85-96	delta like canonical Notch ligand 4	Homo sapiens	176-180	
22883339-8	2012	CONCLUSION: Ang2, Notch1 and Dll4 may correlate with the pathogenesis of GIVM, while thalidomide can concentration-dependently down-regulate the expression of Ang2, Notch1 and Dll4, which may be one of the mechanism that thalidomide play a therapeutic role in GIVM.	Thalidomide	221-232	delta like canonical Notch ligand 4	Homo sapiens	176-180