PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33015978-8 2021 Altered expression of miR-141 and HDAC6 was introduced to identify their functions in thalidomide-mediated events. Thalidomide 86-97 histone deacetylase 6 Rattus norvegicus 34-39 33015978-12 2021 miR-141 was responsible for thalidomide-mediated protective events by targeting HDAC6. Thalidomide 28-39 histone deacetylase 6 Rattus norvegicus 80-85 33015978-13 2021 Overexpression of HDAC6 blocked the protection of thalidomide against PQ-induced injury via activating the IkBalpha-NF-kappaB signalling pathway. Thalidomide 50-61 histone deacetylase 6 Rattus norvegicus 18-23 33015978-14 2021 Collectively, this study evidenced that thalidomide protects lung tissues from PQ-induced injury through a miR-141/HDAC6/IkBalpha-NF-kappaB axis. Thalidomide 40-51 histone deacetylase 6 Rattus norvegicus 115-120