PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21541537-0	1996	Dysregulation of transforming growth factor-beta 1 expression in N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis.	nitrosobenzylmethylamine	65-91	transforming growth factor, beta 1	Rattus norvegicus	17-50	
21541537-2	1996	To further investigate the role of TGF-beta 1 in chemically-induced esophageal tumorigenesis, the expression of TGF-beta 1 was analyzed by reverse transcription-polymerase chain reaction (T-PCR) and immunohistochemical studies in N-nitrosomethylbenzylamine (NMBA)-induced rat esophageal tumorigenesis.	nitrosobenzylmethylamine	230-256	transforming growth factor, beta 1	Rattus norvegicus	112-122	
21541537-4	1996	However, TGF-beta 1 mRNA levels were increased 2.9-fold (p<0.05) in 45-week papillomas induced by NMBA, when compared to normal rat esophageal epithelium.	nitrosobenzylmethylamine	101-105	transforming growth factor, beta 1	Rattus norvegicus	9-19	
21541537-7	1996	These findings suggest that overexpression of TGF-beta 1 mRNA occurs late in NMBA-induced rat esophageal tumorigenesis, and the discordant mRNA and protein expression may result in tumor evasion from TGF-beta 1 controlled negative growth regulation, thus promoting tumor progression in this model.	nitrosobenzylmethylamine	77-81	transforming growth factor, beta 1	Rattus norvegicus	46-56