PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8988237-6 1996 In contrast to the meningioma species, brain G1A AChE forms remained amphiphilic after incubation with alkaline hydroxylamine and phosphatidylinositol-specific phospholipase C (PIPLC). Phosphatidylinositols 130-150 acetylcholinesterase (Cartwright blood group) Homo sapiens 49-53 10530519-4 1999 The AChE dimers and monomers remained amphiphilic after incubation with phosphatidylinositol-specific phospholipase C (PIPLC), after or without prior treatment with alkaline hydroxylamine, which shows that, in contrast to the meningioma AChE dimers and monomers, the neurinoma isoforms are devoid of glycolipid. Phosphatidylinositols 72-92 acetylcholinesterase (Cartwright blood group) Homo sapiens 4-8 10530519-4 1999 The AChE dimers and monomers remained amphiphilic after incubation with phosphatidylinositol-specific phospholipase C (PIPLC), after or without prior treatment with alkaline hydroxylamine, which shows that, in contrast to the meningioma AChE dimers and monomers, the neurinoma isoforms are devoid of glycolipid. Phosphatidylinositols 72-92 acetylcholinesterase (Cartwright blood group) Homo sapiens 237-241 8710179-6 1996 A small fraction of glioma AChE monomers was released as, or transformed into, hydrophilic forms by incubation with phosphatidylinositol-specific phospholipase C (PIPLC). Phosphatidylinositols 116-136 acetylcholinesterase (Cartwright blood group) Homo sapiens 27-31 7478260-3 1995 A significant fraction of the amphiphilic AChE species was converted into hydrophilic components by incubation of the soluble enzyme with phosphatidylinositol-specific phospholipase C (PIPLC) from Bacillus thuringiensis, this fraction being increased by a double treatment with PIPLC and alkaline hydroxylamine. Phosphatidylinositols 138-158 acetylcholinesterase (Cartwright blood group) Homo sapiens 42-46 3593210-2 1987 Our earlier evidence suggested that both acetylcholinesterase and alkaline phosphatase are anchored to the cell surface via covalently-attached phosphatidylinositol [Low, Futerman, Ferguson & Silman (1986) Trends Biochem. Phosphatidylinositols 144-164 acetylcholinesterase (Cartwright blood group) Homo sapiens 41-61 2146267-1 1990 We analyzed the molecular species composition of the glycosylphosphatidylinositol (GPI) anchor of Torpedo marmorata acetylcholinesterase (AChE) and compared it to that of the membrane phosphatidylinositol (PI) as well as the other major phospholipid classes of T. marmorata electrocytes. Phosphatidylinositols 61-81 acetylcholinesterase (Cartwright blood group) Homo sapiens 138-142 2540962-0 1989 Conversion of human erythrocyte acetylcholinesterase from an amphiphilic to a hydrophilic form by phosphatidylinositol-specific phospholipase C and serum phospholipase D. Phosphatidylinositols 98-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 32-52 2540962-8 1989 Deacylation of human erythrocyte AChE by an alkaline treatment with hydroxylamine rendered the amphiphilic AChE susceptible to PtdIns-specific PLC with the consequent release of hydrophilic AChE. Phosphatidylinositols 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 33-37 2540962-8 1989 Deacylation of human erythrocyte AChE by an alkaline treatment with hydroxylamine rendered the amphiphilic AChE susceptible to PtdIns-specific PLC with the consequent release of hydrophilic AChE. Phosphatidylinositols 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-111 2540962-8 1989 Deacylation of human erythrocyte AChE by an alkaline treatment with hydroxylamine rendered the amphiphilic AChE susceptible to PtdIns-specific PLC with the consequent release of hydrophilic AChE. Phosphatidylinositols 127-133 acetylcholinesterase (Cartwright blood group) Homo sapiens 107-111 2451546-3 1988 DAF, AChE, and LAP are known to be anchored within cell membranes to glycophospholipid-containing phosphatidylinositol (PI). Phosphatidylinositols 98-118 acetylcholinesterase (Cartwright blood group) Homo sapiens 5-9 2165068-6 1990 The cDNA encoding hydrophobic acetylcholinesterase directs the synthesis of enzyme with much greater activity, which is expressed on the outer surface of the cell membrane and can be released by phosphatidylinositol-specific phospholipase C. A mutant truncated acetylcholinesterase which lacks either carboxyl-terminal sequence encoded by the alternative exons is secreted into the medium. Phosphatidylinositols 195-215 acetylcholinesterase (Cartwright blood group) Homo sapiens 30-50 2165068-6 1990 The cDNA encoding hydrophobic acetylcholinesterase directs the synthesis of enzyme with much greater activity, which is expressed on the outer surface of the cell membrane and can be released by phosphatidylinositol-specific phospholipase C. A mutant truncated acetylcholinesterase which lacks either carboxyl-terminal sequence encoded by the alternative exons is secreted into the medium. Phosphatidylinositols 195-215 acetylcholinesterase (Cartwright blood group) Homo sapiens 261-281 2298208-4 1990 In Triton X-100 extracts of the subline K562-243, phosphatidylinositol-specific phospholipase C (PtdIns-PLC) from Bacillus thuringiensis converted most of the G2a AChE into a hydrophilic dimer (G2h), indicating that the G2a form possessed a hydrophobic glycoinositol phospholipid that mediated its attachment to the membrane. Phosphatidylinositols 50-70 acetylcholinesterase (Cartwright blood group) Homo sapiens 163-167 2848806-1 1988 Palmitoylation of inositol results in resistance to phosphatidylinositol-specific phospholipase C. The glycoinositol phospholipid membrane anchor of human erythrocyte acetylcholinesterase (EC 3.1.1.7) contains a novel inositol phospholipid which in this and the accompanying paper (Roberts, W.L., Santikarn, S., Reinhold, V.N., and Rosenberry, T.L. Phosphatidylinositols 52-72 acetylcholinesterase (Cartwright blood group) Homo sapiens 167-187 2848806-1 1988 Palmitoylation of inositol results in resistance to phosphatidylinositol-specific phospholipase C. The glycoinositol phospholipid membrane anchor of human erythrocyte acetylcholinesterase (EC 3.1.1.7) contains a novel inositol phospholipid which in this and the accompanying paper (Roberts, W.L., Santikarn, S., Reinhold, V.N., and Rosenberry, T.L. Phosphatidylinositols 108-129 acetylcholinesterase (Cartwright blood group) Homo sapiens 167-187 3933520-0 1985 The solubilization of platelet membrane-bound acetylcholinesterase and aryl acylamidase by exogenous or endogenous phosphatidylinositol specific phospholipase C. Phosphatidylinositol specific phospholipase C from Staphylococcus aureus could solubilize acetylcholinesterase up to 55% from sheep platelets in the presence of ethylenediaminetetra acetic acid (EDTA). Phosphatidylinositols 115-135 acetylcholinesterase (Cartwright blood group) Homo sapiens 46-66 3933520-0 1985 The solubilization of platelet membrane-bound acetylcholinesterase and aryl acylamidase by exogenous or endogenous phosphatidylinositol specific phospholipase C. Phosphatidylinositol specific phospholipase C from Staphylococcus aureus could solubilize acetylcholinesterase up to 55% from sheep platelets in the presence of ethylenediaminetetra acetic acid (EDTA). Phosphatidylinositols 115-135 acetylcholinesterase (Cartwright blood group) Homo sapiens 252-272 3933520-0 1985 The solubilization of platelet membrane-bound acetylcholinesterase and aryl acylamidase by exogenous or endogenous phosphatidylinositol specific phospholipase C. Phosphatidylinositol specific phospholipase C from Staphylococcus aureus could solubilize acetylcholinesterase up to 55% from sheep platelets in the presence of ethylenediaminetetra acetic acid (EDTA). Phosphatidylinositols 162-182 acetylcholinesterase (Cartwright blood group) Homo sapiens 46-66 3933520-0 1985 The solubilization of platelet membrane-bound acetylcholinesterase and aryl acylamidase by exogenous or endogenous phosphatidylinositol specific phospholipase C. Phosphatidylinositol specific phospholipase C from Staphylococcus aureus could solubilize acetylcholinesterase up to 55% from sheep platelets in the presence of ethylenediaminetetra acetic acid (EDTA). Phosphatidylinositols 162-182 acetylcholinesterase (Cartwright blood group) Homo sapiens 252-272 3933520-3 1985 It is suggested that phosphatidylinositol specific phospholipase C will be a useful tool in the solubilization of acetylcholinesterase from mammalian sources and its purification free of detergents. Phosphatidylinositols 21-41 acetylcholinesterase (Cartwright blood group) Homo sapiens 114-134 4045459-0 1985 Solubilization of membrane-bound acetylcholinesterase by a phosphatidylinositol-specific phospholipase C. Phosphatidylinositol-specific phospholipase C (PIPLC) quantitatively solubilizes acetylcholinesterase (AChE) from purified synaptic plasma membranes and intact synaptosomes of Torpedo ocellata electric organ. Phosphatidylinositols 59-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 209-213 4045459-0 1985 Solubilization of membrane-bound acetylcholinesterase by a phosphatidylinositol-specific phospholipase C. Phosphatidylinositol-specific phospholipase C (PIPLC) quantitatively solubilizes acetylcholinesterase (AChE) from purified synaptic plasma membranes and intact synaptosomes of Torpedo ocellata electric organ. Phosphatidylinositols 106-126 acetylcholinesterase (Cartwright blood group) Homo sapiens 209-213 4004881-1 1985 The hydrophobic, membrane-bound form of Torpedo acetylcholinesterase is specifically solubilized by a phosphatidylinositol-specific phospholipase C, suggesting that acetylcholinesterase is bound to the membrane via a direct and specific interaction with phosphatidylinositol (Futerman et al., Biochem. Phosphatidylinositols 102-122 acetylcholinesterase (Cartwright blood group) Homo sapiens 48-68 4004881-1 1985 The hydrophobic, membrane-bound form of Torpedo acetylcholinesterase is specifically solubilized by a phosphatidylinositol-specific phospholipase C, suggesting that acetylcholinesterase is bound to the membrane via a direct and specific interaction with phosphatidylinositol (Futerman et al., Biochem. Phosphatidylinositols 102-122 acetylcholinesterase (Cartwright blood group) Homo sapiens 165-185 4004881-1 1985 The hydrophobic, membrane-bound form of Torpedo acetylcholinesterase is specifically solubilized by a phosphatidylinositol-specific phospholipase C, suggesting that acetylcholinesterase is bound to the membrane via a direct and specific interaction with phosphatidylinositol (Futerman et al., Biochem. Phosphatidylinositols 254-274 acetylcholinesterase (Cartwright blood group) Homo sapiens 48-68 4004881-1 1985 The hydrophobic, membrane-bound form of Torpedo acetylcholinesterase is specifically solubilized by a phosphatidylinositol-specific phospholipase C, suggesting that acetylcholinesterase is bound to the membrane via a direct and specific interaction with phosphatidylinositol (Futerman et al., Biochem. Phosphatidylinositols 254-274 acetylcholinesterase (Cartwright blood group) Homo sapiens 165-185 4004881-6 1985 The results presented strongly support our suggestion that phosphatidylinositol is indeed involved in anchoring acetylcholinesterase to the plasma membrane. Phosphatidylinositols 59-79 acetylcholinesterase (Cartwright blood group) Homo sapiens 112-132 6501251-0 1984 Acetylcholinesterase release from mammalian erythrocytes by phosphatidylinositol-specific phospholipase C of Bacillus thuringiensis and characterization of the released enzyme. Phosphatidylinositols 60-80 acetylcholinesterase (Cartwright blood group) Homo sapiens 0-20 6501251-1 1984 The mode of acetylcholinesterase release from mammalian erythrocyte membranes by the action of phosphatidylinositol(PI)-specific phospholipase C of Bacillus thuringiensis was studied. Phosphatidylinositols 95-115 acetylcholinesterase (Cartwright blood group) Homo sapiens 12-32 913568-0 1977 Non-lytic release of acetylcholinesterase from erythrocytes by a phosphatidylinositol-specific phospholipase C. Phosphatidylinositols 65-85 acetylcholinesterase (Cartwright blood group) Homo sapiens 21-41