PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
8263960-2	1993	In the CCA of the rapid ventricular pacing-overdrive dog model of CHF, elevated plasma endothelin levels were associated with a decrease in the basal accumulation of inositol phosphates and ET-1 mediated activation of phosphatidylinositol (PI) turnover (P < 0.05).	Phosphatidylinositols	218-238	endothelin 1	Canis lupus familiaris	190-194	
15492464-1	2004	Endothelin-1 (ET-1), angiotensin II (Ang II), and phenylephrine, an alpha1-adrenoceptor agonist, share the common signaling process, resulting in activation of Gq protein-coupled receptor (GqPCR) to activate the hydrolysis of phosphoinositide (PI).	Phosphatidylinositols	226-242	endothelin 1	Canis lupus familiaris	0-12	
15492464-1	2004	Endothelin-1 (ET-1), angiotensin II (Ang II), and phenylephrine, an alpha1-adrenoceptor agonist, share the common signaling process, resulting in activation of Gq protein-coupled receptor (GqPCR) to activate the hydrolysis of phosphoinositide (PI).	Phosphatidylinositols	226-242	endothelin 1	Canis lupus familiaris	14-18	
11811352-3	2001	Endothelin-1 and angiotensin II, the Gq protein-coupled receptors (GqPCR) of which are coupled to Gq protein-mediated stimulation of phosphoinositide (PI) hydrolysis as phenylephrine, did not affect the contractile force under control conditions either.	Phosphatidylinositols	133-149	endothelin 1	Canis lupus familiaris	0-31	
7736562-0	1995	Effect of phorbol ester on phosphoinositide hydrolysis and calcium mobilization induced by endothelin-1 in cultured canine tracheal smooth muscle cells.	Phosphatidylinositols	27-43	endothelin 1	Canis lupus familiaris	91-103	
1415620-8	1992	Thus volume-induced secretion of ANF is not suppressed by verapamil, but is directly enhanced by low-dose ET-1, known to activate the phosphoinositide pathway.	Phosphatidylinositols	134-150	endothelin 1	Canis lupus familiaris	106-110	
2473332-0	1989	Endothelin-1 stimulates phosphatidylinositol hydrolysis and calcium uptake in isolated canine coronary arteries.	Phosphatidylinositols	24-44	endothelin 1	Canis lupus familiaris	0-12