PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33753496-7	2021	LTC4-mediated itch differed in bout duration and kinetics from pruritogens histamine, compound 48/80, and chloroquine.	Chloroquine	106-117	itchy, E3 ubiquitin protein ligase	Mus musculus	14-18	
34032210-4	2021	Further, we show that chloroquine-activated CeA neurons play important roles in itch-related comorbidities, including anxiety-like behaviors, but not in some aversive and appetitive behaviors previously ascribed to CeA neurons.	Chloroquine	22-33	itchy, E3 ubiquitin protein ligase	Mus musculus	80-84	
32536619-0	2020	Crotamiton, an Anti-Scabies Agent, Suppresses Histamine- and Chloroquine-Induced Itch Pathways in Sensory Neurons and Alleviates Scratching in Mice.	Chloroquine	61-72	itchy, E3 ubiquitin protein ligase	Mus musculus	81-85	
28842279-5	2017	Disruption of itch signal transmission by depletion of peripheral sensory fibers expressing TRPV1 (transient receptor potential vanilloid subfamily, member 1) attenuated chloroquine-induced CPA.	Chloroquine	170-181	itchy, E3 ubiquitin protein ligase	Mus musculus	14-18	
31824317-8	2019	V1AR antagonists could be used as possible treatments for CQ-induced itch.	Chloroquine	58-60	itchy, E3 ubiquitin protein ligase	Mus musculus	69-73	
31824317-0	2019	Intradermal Injection of Oxytocin Aggravates Chloroquine-Induced Itch Responses via Activating the Vasopressin-1a Receptor/Nitric Oxide Pathway in Mice.	Chloroquine	45-56	itchy, E3 ubiquitin protein ligase	Mus musculus	65-69	
27783328-5	2017	We found that systemic administration of NAC or PBN significantly alleviated compound 48/80- and chloroquine-induced acute itch in a dose-dependent manner, attenuated dry skin-induced chronic itch, and suppressed oxidative stress in the affected skin.	Chloroquine	97-108	itchy, E3 ubiquitin protein ligase	Mus musculus	123-127	
28410268-3	2017	Pretreatment of intradermal BoNT/A exerted long-term inhibitory effects on compound 48/80-induced and chloroquine-induced acute itch on days 1, 3, 7, and 14, but not on day 21, in mice.	Chloroquine	102-113	itchy, E3 ubiquitin protein ligase	Mus musculus	128-132	
28119997-0	2017	Peripheral NMDA Receptor/NO System Blockage Inhibits Itch Responses Induced by Chloroquine in Mice.	Chloroquine	79-90	itchy, E3 ubiquitin protein ligase	Mus musculus	53-57	
28119997-2	2017	Chloroquine-induced itch is histamine-independent and we have reported that the nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) pathway is involved in CQ-induced scratching behavior in mice.	Chloroquine	0-11	itchy, E3 ubiquitin protein ligase	Mus musculus	20-24	
28119997-2	2017	Chloroquine-induced itch is histamine-independent and we have reported that the nitric oxide (NO)/cyclic guanosine monophosphate (cGMP) pathway is involved in CQ-induced scratching behavior in mice.	Chloroquine	159-161	itchy, E3 ubiquitin protein ligase	Mus musculus	20-24	
20004959-0	2009	Sensory neuron-specific GPCR Mrgprs are itch receptors mediating chloroquine-induced pruritus.	Chloroquine	65-76	itchy, E3 ubiquitin protein ligase	Mus musculus	40-44	
20004959-2	2009	Itch induced by chloroquine (CQ) is a common side effect of this widely used antimalarial drug.	Chloroquine	16-27	itchy, E3 ubiquitin protein ligase	Mus musculus	0-4	
20004959-2	2009	Itch induced by chloroquine (CQ) is a common side effect of this widely used antimalarial drug.	Chloroquine	29-31	itchy, E3 ubiquitin protein ligase	Mus musculus	0-4	
20004959-4	2009	Mice lacking a cluster of Mrgpr genes display significant deficits in itch induced by CQ but not histamine.	Chloroquine	86-88	itchy, E3 ubiquitin protein ligase	Mus musculus	70-74	
16697529-6	2006	Finally, a comparison of the strain means obtained here with previously collected data using nociceptive assays revealed a suggestive negative genetic correlation between chloroquine-induced itch and thermal pain, such that strains sensitive to pain are resistant to itch and vice versa.	Chloroquine	171-182	itchy, E3 ubiquitin protein ligase	Mus musculus	191-195	
16697529-6	2006	Finally, a comparison of the strain means obtained here with previously collected data using nociceptive assays revealed a suggestive negative genetic correlation between chloroquine-induced itch and thermal pain, such that strains sensitive to pain are resistant to itch and vice versa.	Chloroquine	171-182	itchy, E3 ubiquitin protein ligase	Mus musculus	267-271