PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 8818396-10 1996 On the contrary, 3 alpha-hydroxysteroid dehydrogenase, the enzyme which converts DHP into 5 alpha-pregnane-3 alpha-ol-20-one (THP), appears to be present mainly in type-1 astrocytes; much lower levels of this enzyme are present in neurons and in type-2 astrocytes. pirarubicin 126-129 aldo-keto reductase family 1, member C14 Rattus norvegicus 17-53 12890523-9 2003 These data suggest that (i) transient increase of neurosteroid biosynthesis may contribute to stress hyporesponsiveness during early infancy; (ii) gonadal steroids regulate 3 alpha-HSD expression in the hippocampus in a sex-specific mode; (iii) physiological sex steroid secretions in females may mask behavioral consequences of adverse early life events, and (iv) concomitant treatment with the neurosteroid THP counteracts behavioral and endocrine dysregulation induced by neonatal stress in both genders. pirarubicin 409-412 aldo-keto reductase family 1, member C14 Rattus norvegicus 173-184