PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 29061786-7 2017 In HP100 cells, THP-induced apoptosis, evaluated by DNA ladder formation, H2O2 generation, mitochondrial membrane potential decrease and caspase-3/7 activity, was suppressed or delayed compared to those of HL-60 cells. pirarubicin 16-19 caspase 3 Homo sapiens 137-146 22198116-0 2012 Anthraquinone antitumour agents, doxorubicin, pirarubicin and benzoperimidine BP1, trigger caspase-3/caspase-8-dependent apoptosis of leukaemia sensitive HL60 and resistant HL60/VINC and HL60/DOX cells. pirarubicin 46-57 caspase 3 Homo sapiens 91-100 11408917-9 2001 Epirubicin and pirarubicin, compounds closely related to ADR, also respectively enhanced 4.2-fold (p = 0.0052) and 2.8-fold (p = 0.0147) caspase-3 activity in ACHN cells. pirarubicin 15-26 caspase 3 Homo sapiens 137-146