PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 25791481-10 2015 Pirarubicin-induced autophagy was mediated via the mTOR/p70S6K/4E-BP1 signaling pathway. pirarubicin 0-11 mechanistic target of rapamycin kinase Homo sapiens 51-55 33065796-12 2020 In addition, compared with the control group, the THP group had significantly higher LC3 protein expression, a significantly higher LC3-II/LC3-I ratio (P<0.05), and significantly lower p-PI3K, p-Akt, and p-mTOR (P<0.05). pirarubicin 50-53 mechanistic target of rapamycin kinase Homo sapiens 206-210 34935899-0 2022 Down-regulating GRP78 reverses pirarubicin resistance of triple negative breast cancer by miR-495-3p mimics and involves the p-AKT/mTOR pathway. pirarubicin 31-42 mechanistic target of rapamycin kinase Homo sapiens 131-135 31138757-0 2019 Low concentration of rutin treatment might alleviate the cardiotoxicity effect of pirarubicin on cardiomyocytes via activation of PI3K/AKT/mTOR signaling pathway. pirarubicin 82-93 mechanistic target of rapamycin kinase Homo sapiens 139-143