PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
16740726-0	2006	Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5.	Glycosides	8-18	TNF receptor superfamily member 10a	Homo sapiens	114-137	
16740726-7	2006	Blocking of up-regulation of DR4 and DR5 alone significantly reduced cell death after combined treatment with cardiac glycosides and Apo2L/TRAIL.	Glycosides	118-128	TNF receptor superfamily member 10a	Homo sapiens	29-32	
16740726-8	2006	Combined silencing of DR4 and DR5 abrogated the ability of cardiac glycosides and Apo2L/TRAIL to induce apoptosis in an additive manner.	Glycosides	67-77	TNF receptor superfamily member 10a	Homo sapiens	22-25	
16740726-9	2006	To our knowledge, this is the first demonstration that glycosides up-regulate DR4 and DR5, thereby reverting the resistance of lung cancer cells to Apo2/TRAIL-induced apoptosis.	Glycosides	55-65	TNF receptor superfamily member 10a	Homo sapiens	78-81	
16740726-9	2006	To our knowledge, this is the first demonstration that glycosides up-regulate DR4 and DR5, thereby reverting the resistance of lung cancer cells to Apo2/TRAIL-induced apoptosis.	Glycosides	55-65	TNF receptor superfamily member 10a	Homo sapiens	148-152