PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27029345-6 2016 Cardiac glycosides constituted a large group of TRAIL-sensitizing compounds, and they were also effective on GBM cells as single agents. Glycosides 8-18 TNF superfamily member 10 Homo sapiens 48-53 16740726-0 2006 Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5. Glycosides 8-18 TNF superfamily member 10 Homo sapiens 28-33 24045365-3 2014 Here, we have shown that digitoxin (DT), a clinically approved cardiac glycoside for heart failure, can induce TRAIL-mediated apoptosis of glioblastoma cells. Glycosides 71-80 TNF superfamily member 10 Homo sapiens 111-116 16740726-9 2006 To our knowledge, this is the first demonstration that glycosides up-regulate DR4 and DR5, thereby reverting the resistance of lung cancer cells to Apo2/TRAIL-induced apoptosis. Glycosides 55-65 TNF superfamily member 10 Homo sapiens 153-158 16740726-0 2006 Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5. Glycosides 8-18 TNF superfamily member 10 Homo sapiens 34-39 16740726-4 2006 Here, we report that cardiac glycosides, which have been used for the treatment of cardiac failure for many years, sensitize lung cancer cells but not normal human peripheral blood mononuclear cells to Apo2L/TRAIL-induced apoptosis. Glycosides 29-39 TNF superfamily member 10 Homo sapiens 202-207 16740726-4 2006 Here, we report that cardiac glycosides, which have been used for the treatment of cardiac failure for many years, sensitize lung cancer cells but not normal human peripheral blood mononuclear cells to Apo2L/TRAIL-induced apoptosis. Glycosides 29-39 TNF superfamily member 10 Homo sapiens 208-213 16740726-5 2006 Sensitization to Apo2L/TRAIL mediated by cardiac glycosides was accompanied by up-regulation of death receptors 4 (DR4) and 5 (DR5) on both RNA and protein levels. Glycosides 49-59 TNF superfamily member 10 Homo sapiens 17-22 16740726-5 2006 Sensitization to Apo2L/TRAIL mediated by cardiac glycosides was accompanied by up-regulation of death receptors 4 (DR4) and 5 (DR5) on both RNA and protein levels. Glycosides 49-59 TNF superfamily member 10 Homo sapiens 23-28