PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31384471-1 2019 Selective analogs of the natural glycoside phloridzin are marketed drugs that reduce hyperglycemia in diabetes by inhibiting the active sodium glucose cotransporter SGLT2 in the kidneys. Glycosides 33-42 solute carrier family 5 member 2 Homo sapiens 165-170 26180128-11 2015 Since the sodium-glucose cotransporter 2 inhibitors share common structural features, notably a glycoside moiety, investigation of drugs in this class for effects on UGT to identify (or exclude) potential drug-drug interactions is warranted. Glycosides 96-105 solute carrier family 5 member 2 Homo sapiens 10-40 25819489-2 2015 Efforts have been made to discover phlorizin-related glycosides with good SGLT2 inhibitory activity. Glycosides 53-63 solute carrier family 5 member 2 Homo sapiens 74-79 20149653-0 2010 C-Aryl glycoside inhibitors of SGLT2: Exploration of sugar modifications including C-5 spirocyclization. Glycosides 7-16 solute carrier family 5 member 2 Homo sapiens 31-36 21090651-2 2010 The best pharmacophore model, generated from eight glycoside inhibitors, was utilized to virtually screen three chemical databases that led to the identification of three non-glycoside SGLT2 inhibitors. Glycosides 51-60 solute carrier family 5 member 2 Homo sapiens 185-190 22919717-5 2012 This review will highlight some recent advances and structure-activity relationships in the discovery and development of SGLT-2 inhibitors including O-glycoside, C-glycoside, C, O-spiro glycoside and non glycosides. Glycosides 204-214 solute carrier family 5 member 2 Homo sapiens 121-127