PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 28895339-11 2016 Glycosides and its main active components such as astragaloside IV, amygdalin, peoniflorin and their combinations can inhibit the cell cycle conversion of VSMC, with the effect against VSMC proliferation, and the mechanisms may be associated with the inhibition of PI3K/Akt, mitogen-activated protein kinase (MAPK) and JAK/STAT signaling pathways. Glycosides 0-10 AKT serine/threonine kinase 1 Rattus norvegicus 270-273 28549860-0 2017 Crude terpene glycoside component from Radix paeoniae rubra protects against isoproterenol-induced myocardial ischemic injury via activation of the PI3K/AKT/mTOR signaling pathway. Glycosides 14-23 AKT serine/threonine kinase 1 Rattus norvegicus 153-156