PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27667854-5 2016 Lastly, a putative mechanism for the metal complex-catalyzed hydrolysis is derived from the experimental evidence pointing at deprotonation of the hydroxyl group at C-2 as a pre-requisite for glycoside hydrolysis. Glycosides 192-201 complement C2 Homo sapiens 165-168 19716123-1 2009 Glycosides of 2-deoxy-sugars, monosaccharides in which the hydroxyl group at C-2 is replaced with a hydrogen atom, occur widely in natural products and therefore have been the subject of intense synthetic activity. Glycosides 0-10 complement C2 Homo sapiens 77-80 14599211-5 2003 In the case of glycosaminoglycan-derived amidyl radicals, evidence has been obtained in studies with model glycosides that these radicals undergo rapid intramolecular abstraction reactions to give carbon-centered radicals at C-2 on the N-acetyl glycosamine rings (via a 1,2-hydrogen atom shift) and at C-4 on the neighboring uronic acid residues (via 1,5-hydrogen atom shifts). Glycosides 107-117 complement C2 Homo sapiens 225-228 18598060-12 2008 Their nucleophilic character at C-2 permits reactions with oxygen, nitrogen, and sulfur electrophiles that under high substrate stereocontrol generally lead to three-membered rings; ring opening under acid catalysis furnishes the corresponding glycosides, whichdepending on the electrophile Xare also employed for 2-deoxyglycoside synthesis. Glycosides 244-254 complement C2 Homo sapiens 32-35 27220076-4 2016 Evaluation of the structure-activity relationship among steroidal glycosides revealed that the structure of spirostanol with an alpha-L-rhamnopyranosyl linked to C-2 of the inner glucopyranosyl residue both play a critical role in the effects of these compounds on the cancer cell lines. Glycosides 66-76 complement C2 Homo sapiens 162-165