PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
35569549-0	2022	Phillyrin attenuates norepinephrine-induced cardiac hypertrophy and inflammatory response by suppressing p38/ERK1/2 MAPK and AKT/NF-kappaB pathways.	phillyrin	0-9	AKT serine/threonine kinase 1	Rattus norvegicus	125-128	
35569549-8	2022	In addition, treatment with phillyrin markedly inhibited the phosphorylation of p38 MAPK, ERK1/2, AKT, and NF-kappaB p65 in heart tissues.	phillyrin	28-37	AKT serine/threonine kinase 1	Rattus norvegicus	98-101	
35569549-9	2022	Furthermore, in NE-treated H9c2 cells, pretreatment with phillyrin clearly attenuated cardiomyocyte hypertrophy, reduced ROS production and inhibited the phosphorylation of p38 MAPK, ERK1/2, AKT, and NF-kappaB p65 in vitro.	phillyrin	57-66	AKT serine/threonine kinase 1	Rattus norvegicus	191-194	
35569549-10	2022	Collectively, our results demonstrate that phillyrin effectively alleviates NE-induced cardiac hypertrophy and inflammatory response by suppressing p38 MAPK/ERK1/2 and AKT/NF-kappaB signaling pathways.	phillyrin	43-52	AKT serine/threonine kinase 1	Rattus norvegicus	168-171