PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
33584263-8	2020	Blocking autophagy activation with 3-methyladenine (3-MA) in rats treated with ghrelin and 6-OHDA showed no notable change in apoptosis-related markers, while blocking autophagosome fusion with lysosomes with chloroquine could notably reverse the downregulation of bax/bcl-2 ratio and cleaved caspase three expression by ghrelin.	3-methyladenine	52-56	BCL2, apoptosis regulator	Rattus norvegicus	269-274	
32299030-8	2020	Moreover, increased Bcl-2 and Bax levels were observed after treatment with an agonist (rapamycin) and antagonist (3MA) of autophagy in high-glucose-cultured cells.	3-methyladenine	115-118	BCL2, apoptosis regulator	Rattus norvegicus	20-25	
31916058-10	2020	Further immunohistochemistry staining and Western blot showed that 3-MA-treated IRI group presented down-regulated Caspase-3 and up-regulated Bcl-2 protein expression with comparison of IRI group (P < 0.05).	3-methyladenine	67-71	BCL2, apoptosis regulator	Rattus norvegicus	142-147	
31807540-12	2019	Moxibustion preconditioning and 3-MA intervention reversed MIRI-induced changes in Beclin 1, Akt, and Bcl-2 expressions.	3-methyladenine	32-36	BCL2, apoptosis regulator	Rattus norvegicus	102-107	
23364609-7	2013	In addition, 3-MA treatment inhibited the antiapoptotic-related protein levels of Bcl-2 and increased the apoptotic-related protein levels of Bad.	3-methyladenine	13-17	BCL2, apoptosis regulator	Rattus norvegicus	82-87	
23029398-10	2012	Conversely, autophagy inhibitor 3-methyladenine (3-MA) attenuated the ischemic insults, inhibited the activation of autophagy, and elevated the expression of anti-apoptotic protein Bcl-2, to an extent comparable to IPOC.	3-methyladenine	32-47	BCL2, apoptosis regulator	Rattus norvegicus	181-186	
23029398-10	2012	Conversely, autophagy inhibitor 3-methyladenine (3-MA) attenuated the ischemic insults, inhibited the activation of autophagy, and elevated the expression of anti-apoptotic protein Bcl-2, to an extent comparable to IPOC.	3-methyladenine	49-53	BCL2, apoptosis regulator	Rattus norvegicus	181-186	
20574158-10	2010	3-MA inhibited OGD-induced the increase in LC3-II and the decline in Bcl-2.	3-methyladenine	0-4	BCL2, apoptosis regulator	Rattus norvegicus	69-74	
19565656-7	2009	Pretreatment with the autophagy inhibitor 3-methyladenine (3-MA) significantly inhibited the 3-NP-induced alterations in beclin 1 and Bcl-2 protein levels.	3-methyladenine	42-57	BCL2, apoptosis regulator	Rattus norvegicus	134-139	
19565656-7	2009	Pretreatment with the autophagy inhibitor 3-methyladenine (3-MA) significantly inhibited the 3-NP-induced alterations in beclin 1 and Bcl-2 protein levels.	3-methyladenine	59-63	BCL2, apoptosis regulator	Rattus norvegicus	134-139	
19565656-10	2009	3-MA also attenuated the 3-NP-induced release of cytochrome c. On the other hand, 3-NP-induced elevations in proapoptotic protein Bax and autophagic protein beclin 1 and LC3-II were significantly enhanced by the Bcl-2-specific inhibitor HA14-1.	3-methyladenine	0-4	BCL2, apoptosis regulator	Rattus norvegicus	212-217	
18567942-10	2008	The neuroprotective effects of 3-MA and Z-FA-fmk were associated with an inhibition on ischemia-induced upregulation of LC3-II and cathepsin B and a partial reversion of ischemia-induced downregulation of cytoprotective Bcl-2.	3-methyladenine	31-35	BCL2, apoptosis regulator	Rattus norvegicus	220-225