PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31196016-0 2019 Evaluation of long-term effectiveness of the use of carglumic acid in patients with propionic acidemia (PA) or methylmalonic acidemia (MMA): study protocol for a randomized controlled trial. carglumic acid 52-66 monocyte to macrophage differentiation associated Homo sapiens 111-139 31196016-3 2019 Here we report the rationale and design of a phase IIIb trial that is aimed at determining the long-term efficacy and safety of carglumic acid in the management of PA and MMA. carglumic acid 128-142 monocyte to macrophage differentiation associated Homo sapiens 171-174 31196016-9 2019 Although retrospective studies have suggested that long-term carglumic acid may be beneficial in the management of PA and MMA, current literature lacks evidence for this indication. carglumic acid 61-75 monocyte to macrophage differentiation associated Homo sapiens 122-125 31196016-10 2019 This clinical trial will determine the long-term safety and efficacy of carglumic acid in the management of PA and MMA. carglumic acid 72-86 monocyte to macrophage differentiation associated Homo sapiens 115-118