PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 34309760-4 2021 We argue that glutaminyl cyclase (QC) may catalyze the pyroglutamate (pGlu)79-alpha-synuclein formation and, thereby, contribute to enhanced aggregation and compromised degradation of alpha-synuclein in human synucleinopathies. Pyrrolidonecarboxylic Acid 55-68 synuclein alpha Homo sapiens 78-93 34641352-3 2021 Glutamic acid can then be quantified specifically by thermal conversion into pyroglutamic acid followed by chemical derivatization of the pyroglutamic acid formed by an analytical protocol based on an OPA-NAC reagent. Pyrrolidonecarboxylic Acid 138-155 synuclein alpha Homo sapiens 205-208