PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
26654818-3	2015	The etiology seems to be a drug-induced reversible inhibition of glutathione synthetase or 5-oxoprolinase leading to elevated serum and urine levels of 5-oxoproline.	Pyrrolidonecarboxylic Acid	152-164	glutathione synthetase	Homo sapiens	65-87	
18072147-7	2007	DISCUSSION: Originally described in children with an inherited defect of glutathione synthetase, 5-oxoproline is an unusual cause of metabolic acidosis.	Pyrrolidonecarboxylic Acid	97-109	glutathione synthetase	Homo sapiens	73-95	
8896573-1	1996	5-Oxoprolinuria (pyroglutamic aciduria) resulting from glutathione synthetase (GSS) deficiency is an inherited autosomal recessive disorder characterized, in its severe form, by massive urinary excretion of 5-oxoproline, metabolic acidosis, haemolytic anaemia and central nervous system damage.	Pyrrolidonecarboxylic Acid	207-219	glutathione synthetase	Homo sapiens	55-77	
8896573-1	1996	5-Oxoprolinuria (pyroglutamic aciduria) resulting from glutathione synthetase (GSS) deficiency is an inherited autosomal recessive disorder characterized, in its severe form, by massive urinary excretion of 5-oxoproline, metabolic acidosis, haemolytic anaemia and central nervous system damage.	Pyrrolidonecarboxylic Acid	207-219	glutathione synthetase	Homo sapiens	79-82	
28267090-6	2018	Her 5-oxoproline level was 3815 mmol/mol creatinine in urine organic acid analysis, and a homozygous mutation [p.R125H (c.374G>A)] was found in the glutathione synthetase gene.	Pyrrolidonecarboxylic Acid	4-16	glutathione synthetase	Homo sapiens	151-173	
34791353-3	2022	Herein, we present a case of a newborn boy with the most severe phenotype of GSS deficiency, diagnosed based on clinical features and increased urinary 5-oxoproline levels determined via gas chromatography mass spectrometry (GCMS) testing.	Pyrrolidonecarboxylic Acid	152-164	glutathione synthetase	Homo sapiens	77-80	
3676243-4	1987	Glycine is one substrate for the enzyme glutathione synthase (EC 6.3.2.3) and in the inborn error of metabolism in which glutathione synthase function is defective, increased quantities of 5-oxoproline are excreted in the urine.	Pyrrolidonecarboxylic Acid	189-201	glutathione synthetase	Homo sapiens	40-60	
3676243-4	1987	Glycine is one substrate for the enzyme glutathione synthase (EC 6.3.2.3) and in the inborn error of metabolism in which glutathione synthase function is defective, increased quantities of 5-oxoproline are excreted in the urine.	Pyrrolidonecarboxylic Acid	189-201	glutathione synthetase	Homo sapiens	121-141