PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 32886767-7 2020 The end product of Chac1 action is 5-oxoproline, and studies with 5-oxoprolinase (OPLAH), an enzyme of the glutathione cycle has revealed that down-regulation of OPLAH can lead to the accumulation of 5-oxproline which is an important factor in heart failure. Pyrrolidonecarboxylic Acid 35-47 ChaC glutathione specific gamma-glutamylcyclotransferase 1 Homo sapiens 19-24