PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
34051623-1	2021	"Don"t eat me" signal of CD47 is activated via its interaction with SIRPalpha protein on myeloid cells, especially phagocytic cells, and prevents malignant cells from anti-tumor immunity in which pyroglutamate modification of CD47 by glutaminyl-peptide cyclotransferase-like protein (isoQC) takes an important part evidenced by our previous report that isoQC is an essential regulator for CD47-SIRPalpha axis with a strong inhibition on macrophage-mediated phagoctyosis.	Pyrrolidonecarboxylic Acid	196-209	glutaminyl-peptide cyclotransferase like	Homo sapiens	234-282	
34051623-1	2021	"Don"t eat me" signal of CD47 is activated via its interaction with SIRPalpha protein on myeloid cells, especially phagocytic cells, and prevents malignant cells from anti-tumor immunity in which pyroglutamate modification of CD47 by glutaminyl-peptide cyclotransferase-like protein (isoQC) takes an important part evidenced by our previous report that isoQC is an essential regulator for CD47-SIRPalpha axis with a strong inhibition on macrophage-mediated phagoctyosis.	Pyrrolidonecarboxylic Acid	196-209	glutaminyl-peptide cyclotransferase like	Homo sapiens	284-289	
34051623-1	2021	"Don"t eat me" signal of CD47 is activated via its interaction with SIRPalpha protein on myeloid cells, especially phagocytic cells, and prevents malignant cells from anti-tumor immunity in which pyroglutamate modification of CD47 by glutaminyl-peptide cyclotransferase-like protein (isoQC) takes an important part evidenced by our previous report that isoQC is an essential regulator for CD47-SIRPalpha axis with a strong inhibition on macrophage-mediated phagoctyosis.	Pyrrolidonecarboxylic Acid	196-209	glutaminyl-peptide cyclotransferase like	Homo sapiens	353-358	
25666182-3	2015	Two putative substrates of isoQC, N-truncated Abeta peptides and the monocyte chemoattractant chemokine CCL2, undergo isoQC-catalyzed pyroglutamate (pGlu) modification.	Pyrrolidonecarboxylic Acid	134-147	glutaminyl-peptide cyclotransferase like	Homo sapiens	27-32	
25666182-3	2015	Two putative substrates of isoQC, N-truncated Abeta peptides and the monocyte chemoattractant chemokine CCL2, undergo isoQC-catalyzed pyroglutamate (pGlu) modification.	Pyrrolidonecarboxylic Acid	134-147	glutaminyl-peptide cyclotransferase like	Homo sapiens	118-123	
23183267-3	2013	Recently, we showed that the N-terminus of CCL2 is modified to a pyroglutamate (pE)-residue by both glutaminyl cyclases (QC (QPCT)) and its isoenzyme (isoQC (QPCTL)).	Pyrrolidonecarboxylic Acid	65-78	glutaminyl-peptide cyclotransferase like	Homo sapiens	151-156	
23183267-3	2013	Recently, we showed that the N-terminus of CCL2 is modified to a pyroglutamate (pE)-residue by both glutaminyl cyclases (QC (QPCT)) and its isoenzyme (isoQC (QPCTL)).	Pyrrolidonecarboxylic Acid	65-78	glutaminyl-peptide cyclotransferase like	Homo sapiens	158-163	
19804409-13	2009	The functions of QCs and isoQC probably complement each other, suggesting a pivotal role of pyroglutamate modification for protein and peptide maturation.	Pyrrolidonecarboxylic Acid	92-105	glutaminyl-peptide cyclotransferase like	Homo sapiens	25-30	
33159802-3	2021	The N-terminal glutamine on immature CCL2 is replaced with pyroglutamate (pE) by glutaminyl cyclase (QC) and isoQC.	Pyrrolidonecarboxylic Acid	59-72	glutaminyl-peptide cyclotransferase like	Homo sapiens	109-114	
33159802-3	2021	The N-terminal glutamine on immature CCL2 is replaced with pyroglutamate (pE) by glutaminyl cyclase (QC) and isoQC.	Pyrrolidonecarboxylic Acid	74-76	glutaminyl-peptide cyclotransferase like	Homo sapiens	109-114	
23183267-3	2013	Recently, we showed that the N-terminus of CCL2 is modified to a pyroglutamate (pE)-residue by both glutaminyl cyclases (QC (QPCT)) and its isoenzyme (isoQC (QPCTL)).	Pyrrolidonecarboxylic Acid	80-82	glutaminyl-peptide cyclotransferase like	Homo sapiens	151-156	
23183267-3	2013	Recently, we showed that the N-terminus of CCL2 is modified to a pyroglutamate (pE)-residue by both glutaminyl cyclases (QC (QPCT)) and its isoenzyme (isoQC (QPCTL)).	Pyrrolidonecarboxylic Acid	80-82	glutaminyl-peptide cyclotransferase like	Homo sapiens	158-163