PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33462753-5 2021 Filaggrin is degraded by caspase-14, calpain 1, and bleomycin hydrolases into amino acids and amino acid metabolites such as trans-urocanic acid and pyrrolidone carboxylic acid, which are pivotal natural moisturizing factors in the SC. Pyrrolidonecarboxylic Acid 149-176 calpain 1 Homo sapiens 37-46