PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
22874563-3	2012	We have demonstrated that human and mouse CF airways are autophagy deficient due to functional sequestration of BECN1 and that the tissue transglutaminase-2 inhibitor, cystamine, or antioxidants restore BECN1-dependent autophagy and reduce SQSTM1/p62 levels, thus favoring DeltaF508-CFTR trafficking to the epithelial surface.	Cystamine	168-177	beclin 1, autophagy related	Mus musculus	112-117	
22874563-3	2012	We have demonstrated that human and mouse CF airways are autophagy deficient due to functional sequestration of BECN1 and that the tissue transglutaminase-2 inhibitor, cystamine, or antioxidants restore BECN1-dependent autophagy and reduce SQSTM1/p62 levels, thus favoring DeltaF508-CFTR trafficking to the epithelial surface.	Cystamine	168-177	beclin 1, autophagy related	Mus musculus	203-208	
20711182-5	2010	Restoration of beclin 1 and autophagy by either beclin 1 overexpression, cystamine or antioxidants rescues the localization of the beclin 1 interactome to the endoplasmic reticulum and reverts the CF airway phenotype in vitro, in vivo in Scnn1b-transgenic and Cftr(F508del) homozygous mice, and in human CF nasal biopsies.	Cystamine	73-82	beclin 1, autophagy related	Mus musculus	15-23