PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
23904594-6	2013	Moreover, PDI inhibitors, such as cystamine and securinine, caused a selective decrease of orexin neurons and promoted formation of orexin-A-IR aggregates.	Cystamine	34-43	hypocretin	Mus musculus	91-97	
23904594-6	2013	Moreover, PDI inhibitors, such as cystamine and securinine, caused a selective decrease of orexin neurons and promoted formation of orexin-A-IR aggregates.	Cystamine	34-43	hypocretin	Mus musculus	132-138	
28549585-0	2017	Cystamine-mediated inhibition of protein disulfide isomerase triggers aggregation of misfolded orexin-A in the Golgi apparatus and prevents extracellular secretion of orexin-A.	Cystamine	0-9	hypocretin	Mus musculus	95-103	
28549585-11	2017	Moreover, cystamine triggered aggregation of orexin-A, but not orexin-B in the Golgi apparatus of hypothalamic slice cultures and in vivo mouse brains.	Cystamine	10-19	hypocretin	Mus musculus	45-53	
28549585-13	2017	Finally, we demonstrated that cystamine significantly decreased extracellular secretion of orexin-A in AD293 cells overexpressing prepro-orexin.	Cystamine	30-39	hypocretin	Mus musculus	91-99	
28549585-14	2017	These findings suggest that cystamine-induced PDI inhibition induces selective depletion, aggregation in the Golgi apparatus and impaired secretion of orexin-A.	Cystamine	28-37	hypocretin	Mus musculus	151-159	
28549585-0	2017	Cystamine-mediated inhibition of protein disulfide isomerase triggers aggregation of misfolded orexin-A in the Golgi apparatus and prevents extracellular secretion of orexin-A.	Cystamine	0-9	hypocretin	Mus musculus	167-175