PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 24299604-9 2013 RT-PCR and immunoblot studies revealed that myricanone activated the apoptotic signalling cascades through down-regulation of transcription factors like nuclear factor-kappaB (NF-kappaB) (p65), and signal transducers and activators of transcription 3 (STAT3); cell cycle regulators like cyclin D1, and survivin and other signal proteins like Bcl-2 and up-regulation of Bax, caspase-9 and caspase-3. myricanone 44-54 caspase 9 Homo sapiens 374-383