PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
27771902-10	2017	Trolox  also inhibited the phosphorylation of Akt and ERK1/2, which are involved in differentiation and survival, respectively, of these cells.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	0-6	AKT serine/threonine kinase 1	Homo sapiens	46-49	
24556678-9	2014	Furthermore, thioridazine increased the production of reactive oxygen species (ROS) in Caki cells, and ROS scavengers (N-acetylcysteine, glutathione ethyl ester, and trolox) inhibited thioridazine plus TRAIL-induced apoptosis, as well as Akt inhibition and the downregulation of c-FLIP(L) and Mcl-1.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	166-172	AKT serine/threonine kinase 1	Homo sapiens	238-241	
22797316-9	2012	Antioxidant Trolox did not restore IGF-1 signaling, but it increased Akt phosphorylation and also increased cell viability.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	12-18	AKT serine/threonine kinase 1	Homo sapiens	69-72	
28710022-4	2017	Taxifolin, N-acetylcysteine, trolox, Akt inhibitor and Bay11-7085 attenuated the cholesterol oxidation product-induced changes in the apoptosis-related protein levels, activation of the Akt and NF-kappaB, reactive oxygen species production, GSH depletion and cell death.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	29-35	AKT serine/threonine kinase 1	Homo sapiens	186-189	
32261335-7	2013	Furthermore, Se@Trolox effectively blocked the cisplatin-induced reactive oxygen species (ROS) accumulation, activation of AKT and MAPK signaling and DNA damage-mediated p53 phosphorylation in HK-2 cells.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	16-22	AKT serine/threonine kinase 1	Homo sapiens	123-126	
17341418-12	2007	Furthermore, Trolox attenuated indomethacin-induced increased phosphorylation in ERK, p38 MAPK, JNK, and AKT.	6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid	13-19	AKT serine/threonine kinase 1	Homo sapiens	105-108