PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11970953-5	2002	We also show that platelets from mice lacking G(alpha)(i2), which couples to the ADP receptor, P2Y12, exhibit reduced Rap1 activation in response to ADP.	Adenosine Diphosphate	81-84	RAS-related protein 1a	Mus musculus	118-122	
11970953-6	2002	In contrast, platelets from mice that lack G(alpha)(q) show no decrease in the ability to activate Rap1 in response to epinephrine but show a partial reduction in ADP-stimulated Rap1 activation.	Adenosine Diphosphate	163-166	RAS-related protein 1a	Mus musculus	178-182	
22996695-7	2012	In platelets, ADP stimulation of P2RY12 resulted in GTPase Ras-related protein (RAP1) activation and subsequent alphaIIbbeta3 integrin activation.	Adenosine Diphosphate	14-17	RAS-related protein 1a	Mus musculus	80-84	
26988592-3	2016	Our recent work identified 2 independent, yet synergistic, signaling pathways that lead to the activation of the small GTPase Rap1; one mediated by the guanine nucleotide exchange factor, CalDAG-GEFI (CDGI), the other by P2Y12, a platelet receptor for adenosine diphosphate and the target of antiplatelet drugs.	Adenosine Diphosphate	252-273	RAS-related protein 1a	Mus musculus	126-130	
22996695-8	2012	Likewise, we found that ADP stimulation induced RAP1 activation in WT and integrin beta3 gene knockout (Itgb3-/-) OCs, but its effects were substantially blunted in P2ry12-/- OCs.	Adenosine Diphosphate	24-27	RAS-related protein 1a	Mus musculus	48-52