PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
9591927-4	1998	RESULT AND CONCLUSIONS: Diltiazem caused significant venodilation at a dose of 0.01 microg x min(-1) or more, while verapamil and nicardipine only caused this effect at 1 microg x min(-1) or more.	Diltiazem	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	93-99	
25731063-7	2014	Then, diltiazem (0.5 mug x kg(-1) x min(-1)) was continuously administered, and the infusion rate of remifentanil was increased to 0.3 mug x kg(-1) x min(-1).	Diltiazem	6-15	CD59 molecule (CD59 blood group)	Homo sapiens	36-42	
9591927-4	1998	RESULT AND CONCLUSIONS: Diltiazem caused significant venodilation at a dose of 0.01 microg x min(-1) or more, while verapamil and nicardipine only caused this effect at 1 microg x min(-1) or more.	Diltiazem	24-33	CD59 molecule (CD59 blood group)	Homo sapiens	180-186	
7939378-4	1994	Treatment with diltiazem induced a non-significant reduction in heart rate with 3 beats min-1 and decreased blood pressure (-11/-9 mm Hg, p < 0.001).	Diltiazem	15-24	CD59 molecule (CD59 blood group)	Homo sapiens	88-93	
8752192-5	1996	Diltiazem induced a systemic vasodilation (cardiac index: 3.4 +/- 1.0 to 4.0 +/- 1.0 L x min(-1) x m(-2), p = 0.003; aortic systolic pressure: 116 +/- 16 to 107 +/- 19 mm Hg, p = 0.007; systemic resistance index: 676 +/- 235 to 532 +/- 193 dynes x s x cm(-5) x m(-2), p = 0.006), not associated with changes in the LV outflow tract gradient.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	89-95	
9223891-3	1997	The prophylactic intravenous diltiazem infusion (1.0 micrograms.kg-1.min-1) was started immediately after induction of general anesthesia or epidural analgesia and continued until the end of operation.	Diltiazem	29-38	CD59 molecule (CD59 blood group)	Homo sapiens	69-74	
9185464-3	1997	In the diltiazem group continuous intravenous infusion of diltiazem (1-3mcg.kg-1.min-1) was started when the patient"s heart rate remained over 110.min-1 without any predisposing factor.	Diltiazem	58-67	CD59 molecule (CD59 blood group)	Homo sapiens	81-86	
9185464-3	1997	In the diltiazem group continuous intravenous infusion of diltiazem (1-3mcg.kg-1.min-1) was started when the patient"s heart rate remained over 110.min-1 without any predisposing factor.	Diltiazem	58-67	CD59 molecule (CD59 blood group)	Homo sapiens	148-153	
8838433-12	1996	Diltiazem (n = 14) lowered day systolic blood pressure by 13 +/- 2 mmHg, diastolic blood pressure by 11 +/- 2 mmHg and heart rate by 10 +/- 2 beats min-1.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	148-153	
7776513-6	1995	Diltiazem infusion of 4 mcg.kg-1.min-1 decreased the vecuronium infusion rate by 45% compared with 2 other groups.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	33-38	
7776513-7	1995	Plasma diltiazem concentrations in patients receiving 4 mcg.kg-1.min-1 were significantly higher than those receiving 2 mcg.kg-1.min-1.	Diltiazem	7-16	CD59 molecule (CD59 blood group)	Homo sapiens	65-70	
7776513-8	1995	In conclusion diltiazem 4 mcg.kg-1.min-1 potentiates the neuromuscular blockade of vecuronium and it relates with the plasma diltiazem concentration.	Diltiazem	14-23	CD59 molecule (CD59 blood group)	Homo sapiens	35-40	
7776513-8	1995	In conclusion diltiazem 4 mcg.kg-1.min-1 potentiates the neuromuscular blockade of vecuronium and it relates with the plasma diltiazem concentration.	Diltiazem	125-134	CD59 molecule (CD59 blood group)	Homo sapiens	35-40	
8015171-7	1994	Balanced anesthesia with analgesics, vecuronium bromide and calcium blocker (diltiazem 0.5 microgram.kg-1.min-1) had been advocated to maintain the stable circulatory state.	Diltiazem	77-86	CD59 molecule (CD59 blood group)	Homo sapiens	106-111	
3604896-5	1987	In individuals with pretreatment glomerular filtration rates less than or equal to 80 ml/min/1.73m2, diltiazem monotherapy showed both short-term and long-term improvement in glomerular filtration rate (62%) and effective renal plasma flow (34%).	Diltiazem	101-110	CD59 molecule (CD59 blood group)	Homo sapiens	89-94	
2792166-6	1989	In these 6 volunteers, intake of diltiazem (240 mg daily), concurrently with rifampicin for a week, significantly elevated theophylline half-life to 6.2 h as well as reduced its clearance to 1.03 ml.min-1.kg-1.	Diltiazem	33-42	CD59 molecule (CD59 blood group)	Homo sapiens	199-204	
8395510-5	1993	Half-logarithmic plots were linear with rate constants of 0.0058, 0.011, 0.015, and 0.020 min-1 when 3, 10, 30, and 50 microM (+)-cis-diltiazem was added, respectively.	Diltiazem	126-143	CD59 molecule (CD59 blood group)	Homo sapiens	90-95	
1495189-5	1992	Diltiazem was administered i. v. at a rate of 3 micrograms.kg-1.min-1 before induction of anesthesia.	Diltiazem	0-9	CD59 molecule (CD59 blood group)	Homo sapiens	64-69	
1495189-9	1992	Hypertension during the manipulation of the tumor was controlled by increasing the inspired concentration of enflurane or by increasing the infusion rate of diltiazem to 5 micrograms.kg-1.min-1.	Diltiazem	157-166	CD59 molecule (CD59 blood group)	Homo sapiens	188-193	
2635255-5	1989	Both diltiazem and atenolol significantly decreased heart rate at peak effort but the decrease was much more pronounced after atenolol (-52 b.min-1) than after diltiazem (-6 b.min-1).	Diltiazem	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	142-147	
2635255-5	1989	Both diltiazem and atenolol significantly decreased heart rate at peak effort but the decrease was much more pronounced after atenolol (-52 b.min-1) than after diltiazem (-6 b.min-1).	Diltiazem	5-14	CD59 molecule (CD59 blood group)	Homo sapiens	176-181	
3578945-1	1987	An elderly patient, receiving long-term oral diltiazem at the usual dosage, presented a sudden attack of junctional bradycardia at 35 b X min-1; this was badly tolerated by the patient.	Diltiazem	45-54	CD59 molecule (CD59 blood group)	Homo sapiens	138-143	
3949375-6	1986	In subjects with pretreatment glomerular filtration rates of 80 ml/min/1.73 m2 or less, diltiazem therapy was associated with marked improvement in glomerular filtration rate (48%) and effective renal plasma flow (36%).	Diltiazem	88-97	CD59 molecule (CD59 blood group)	Homo sapiens	67-72