PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 21768780-5 2011 The atorvastatin-induced elevation of LC3-II was inhibited by both the translational and the transcriptional inhibitors, suggesting that the inhibition of geranylgeranyl biosynthesis by atorvastatin activates transcription of LC3, which results in elevation of LC3-II and activation of autophagy. geranylgeranyl 155-169 microtubule associated protein 1 light chain 3 alpha Homo sapiens 38-41 21768780-5 2011 The atorvastatin-induced elevation of LC3-II was inhibited by both the translational and the transcriptional inhibitors, suggesting that the inhibition of geranylgeranyl biosynthesis by atorvastatin activates transcription of LC3, which results in elevation of LC3-II and activation of autophagy. geranylgeranyl 155-169 microtubule associated protein 1 light chain 3 alpha Homo sapiens 226-229 21768780-5 2011 The atorvastatin-induced elevation of LC3-II was inhibited by both the translational and the transcriptional inhibitors, suggesting that the inhibition of geranylgeranyl biosynthesis by atorvastatin activates transcription of LC3, which results in elevation of LC3-II and activation of autophagy. geranylgeranyl 155-169 microtubule associated protein 1 light chain 3 alpha Homo sapiens 226-229 21768780-6 2011 RT-PCR and quantitative PCR assays showed that atorvastatin enhanced expression of LC3 mRNA, and addition of geranylgeraniol along with atorvastatin to the medium eliminated the enhancement, confirming the activation of transcription of LC3 is caused by atorvastatin-mediated inhibition of geranylgeranyl biosynthesis. geranylgeranyl 290-304 microtubule associated protein 1 light chain 3 alpha Homo sapiens 237-240