PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 20650986-0 2011 Steroids induce a disequilibrium of secreted interleukin-1 receptor antagonist and interleukin-1beta synthesis by human neutrophils. Steroids 0-8 interleukin 1 receptor antagonist Homo sapiens 45-78 32631210-5 2020 We describe two cases where anakinra (human recombinant interleukin-1 receptor antagonist) was used as steroid-sparing therapy for life-threatening protracted paradoxical inflammation in HIV-associated TB. Steroids 103-110 interleukin 1 receptor antagonist Homo sapiens 56-89 32398478-1 2020 Interleukin-1 (IL-1) receptor antagonist (anakinra) has been shown to be effective in steroid-dependent recurrent pericarditis resistant to nonsteroidal anti-inflammatory drugs (NSAIDs) and colchicine. Steroids 86-93 interleukin 1 receptor antagonist Homo sapiens 15-40 20975573-0 2011 Interleukin 1 beta (IL-1B) and IL-1 antagonist receptor (IL-1RN) gene polymorphisms are associated with the genetic susceptibility and steroid dependence in patients with ulcerative colitis. Steroids 135-142 interleukin 1 receptor antagonist Homo sapiens 57-63 20975573-9 2011 CONCLUSIONS: IL-1 RN and IL-1B polymorphisms were associated with the genetic susceptibility to develop UC and might be associated with the presence of steroid-dependence in UC patients. Steroids 152-159 interleukin 1 receptor antagonist Homo sapiens 13-20 20538031-9 2010 The higher doses of glucocorticosteroids needed in active LN could be due to steroid resistance and IL-1Ra polymorphism. Steroids 32-39 interleukin 1 receptor antagonist Homo sapiens 100-106 15242697-3 2004 Steroids modulate some plasma cytokines (decreasing TNFalpha, IL-8, IL-6 and increasing IL-10), whereas ability to reduce plasma and urinary TNFsr-2 and IL-1ra and peri-operative renal injury is unknown. Steroids 0-8 interleukin 1 receptor antagonist Homo sapiens 153-159 19162335-0 2009 The analysis of IL-1 beta and its naturally occurring inhibitors in multiple sclerosis: The elevation of IL-1 receptor antagonist and IL-1 receptor type II after steroid therapy. Steroids 162-169 interleukin 1 receptor antagonist Homo sapiens 105-129 19162335-3 2009 IL-1Ra and/or IL-1 RII increased in sera of all 10 investigated patients after the steroid treatment for relapse. Steroids 83-90 interleukin 1 receptor antagonist Homo sapiens 0-6 35525835-12 2022 CONCLUSIONS: PMX-DHP combined with steroid pulse therapy might reduce GRO, IL-10, IL-1Ra, IL-5, IL-6, and MCP-1 levels in ARF, contributing to better oxygenation in the disorder. Steroids 35-42 interleukin 1 receptor antagonist Homo sapiens 82-88 14519149-10 2003 In addition, the observation that budesonide-treatment may result in higher nasal IL-1ra levels supports the hypothesis that steroids act in part by increasing the endogenous anti-inflammatory screen. Steroids 125-133 interleukin 1 receptor antagonist Homo sapiens 82-88 12568852-5 2003 INTERVENTION(S): Confluent stromal cell cultures treated with steroid hormones were stimulated with IL-1beta and attenuated by anti-IL-1beta antibody or IL-1 receptor antagonist. Steroids 62-78 interleukin 1 receptor antagonist Homo sapiens 153-177 11073827-7 2000 However, IL-1Ra production was lower in steroid-resistant than in steroid-responsive rejection, and this difference was still observed 2 years after rejection. Steroids 40-47 interleukin 1 receptor antagonist Homo sapiens 9-15 11073827-7 2000 However, IL-1Ra production was lower in steroid-resistant than in steroid-responsive rejection, and this difference was still observed 2 years after rejection. Steroids 66-73 interleukin 1 receptor antagonist Homo sapiens 9-15 11073827-9 2000 Low IL-1Ra production is associated with steroid resistance of acute rejection and is due to a constitutional defect. Steroids 41-48 interleukin 1 receptor antagonist Homo sapiens 4-10 8049450-4 1994 We performed an open-label, phase I/II trial to evaluate the safety and efficacy of IL-1Ra in 17 patients with steroid-resistant GVHD. Steroids 111-118 interleukin 1 receptor antagonist Homo sapiens 84-90