PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22155565-1 2012 The ovarian steroid progesterone, acting through the progesterone receptor (PR), coordinates endometrial epithelial-stromal cell communication, which is critical for its development and function. Steroids 12-19 progesterone receptor Mus musculus 53-74 22155565-1 2012 The ovarian steroid progesterone, acting through the progesterone receptor (PR), coordinates endometrial epithelial-stromal cell communication, which is critical for its development and function. Steroids 12-19 progesterone receptor Mus musculus 76-78 18280760-3 2008 These events in early pregnancy are tightly regulated by the steroid hormones, estrogen (E2) and progesterone (P4), through their cognate receptors, the estrogen receptor (ER) and the progesterone receptor (PR), respectively. Steroids 61-68 progesterone receptor Mus musculus 184-205 18625316-7 2008 Progesterone and R5020 had similar IC(50) values; steroids 8a, 8f and 8c bind to the progesterone receptor with RBAs of 100%, whereas 8e, 8b and 8d have RBA values <100%. Steroids 50-58 progesterone receptor Mus musculus 85-106 18625316-9 2008 Having demonstrated in this study that steroids 8a-8f bind to the PR, we also evaluated the receptor"s selectivity, since some progesterone derivatives bind to AR, MR, GR receptors. Steroids 39-47 progesterone receptor Mus musculus 66-68 18625316-17 2008 The overall data showed that steroids 8a, 8f, 8e and 8c have a high and selective binding activity to the PR. Steroids 29-37 progesterone receptor Mus musculus 106-108 18280760-3 2008 These events in early pregnancy are tightly regulated by the steroid hormones, estrogen (E2) and progesterone (P4), through their cognate receptors, the estrogen receptor (ER) and the progesterone receptor (PR), respectively. Steroids 61-68 progesterone receptor Mus musculus 207-209 16899559-2 2006 In this study, the mPRalpha and mPRbeta isoforms from zebrafish were shown to be rapidly and specifically activated by the maturation-inducing steroid (MIS) of this species, 4-pregnen-17,20beta-diol-3-one (17,20beta-DHP). Steroids 143-150 progesterone receptor Mus musculus 32-39 2069958-6 1991 The murine progesterone receptor had complete identity for the DNA binding domain of human and rabbit progesterone receptors and 99% homology with the chicken progesterone receptor; for the steroid binding domain, it had 96% homology with human and rabbit progesterone receptors and 86% homology with chicken progesterone receptors. Steroids 190-197 progesterone receptor Mus musculus 11-32 15329476-12 2004 E2 stimulated the expression levels of ERalpha and PR mRNAs and P4 inhibited the expression of these transcripts at an early time point (12 h) and increased them at 24 and 48 h, while co-treatments with both steroids increased transcripts of ERalpha and PR at 24 h. In conclusion, P4 and PR may be dominant factors in the regulation of CaBP-9k. Steroids 208-216 progesterone receptor Mus musculus 51-53 15329476-12 2004 E2 stimulated the expression levels of ERalpha and PR mRNAs and P4 inhibited the expression of these transcripts at an early time point (12 h) and increased them at 24 and 48 h, while co-treatments with both steroids increased transcripts of ERalpha and PR at 24 h. In conclusion, P4 and PR may be dominant factors in the regulation of CaBP-9k. Steroids 208-216 progesterone receptor Mus musculus 254-256 10707954-6 2000 The overexpression and disrupted cellular distribution of PR in C/EBPbeta-/- mice were coincident with a striking 10-fold decrease in cell proliferation after acute steroid hormone treatment, assayed by incorporation of bromodeoxyuridine. Steroids 165-180 progesterone receptor Mus musculus 58-60 33158280-1 2020 The selective progesterone receptor modulator mifepristone (MF) may act as a potent antiproliferative agent in different steroid-dependent cancers due to its strong antagonistic effect on the nuclear progesterone receptor (PGR). Steroids 121-128 progesterone receptor Mus musculus 14-35 35508278-4 2022 In the present study, we provide evidence for the insulin-sensitizing role of smoothelin-like protein 1 (SMTNL1) that is a ligand-dependent co-regulator of steroid receptors, predominantly the progesterone receptor. Steroids 156-163 progesterone receptor Mus musculus 193-214 26465008-7 2015 In summary, these novel findings indicate that estrogens differentially regulate PR-A and PR-B expression in the female hypothalamus, and provide a mechanism by which steroid action in brain can selectively modulate behavior and physiology. Steroids 167-174 progesterone receptor Mus musculus 90-94 31566189-4 2019 In addition, cells were treated with mifepristone (RU486), a synthetic steroid that has an affinity for progesterone receptor (Pgr), for one day starting on day 11. Steroids 71-78 progesterone receptor Mus musculus 104-125 31566189-4 2019 In addition, cells were treated with mifepristone (RU486), a synthetic steroid that has an affinity for progesterone receptor (Pgr), for one day starting on day 11. Steroids 71-78 progesterone receptor Mus musculus 127-130 25904015-2 2015 Steroid hormone-responsive tissues express multiple KLFs that are linked to progesterone receptor (PGR) and estrogen receptor (ESR) actions either as integrators or as coregulators. Steroids 0-15 progesterone receptor Mus musculus 76-97 25904015-2 2015 Steroid hormone-responsive tissues express multiple KLFs that are linked to progesterone receptor (PGR) and estrogen receptor (ESR) actions either as integrators or as coregulators. Steroids 0-15 progesterone receptor Mus musculus 99-102 24489989-5 2014 Moreover, analysis of the uterine phenotypes of ERalpha/ERbeta and PRA/PRB knockout mice indicates that different ER subtypes and PR isoforms mediate distinct responses to steroid hormones and play different roles in uterine function. Steroids 172-188 progesterone receptor Mus musculus 71-74