PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 2939095-8 1986 The CDP reductase activity in the PFA 3-9 cells decreased to wild-type control levels, and the CDP reductase activity of wild-type cells was also greatly reduced when PFA (2-3 mM) was added to permeabilized cells during the enzyme assay. Foscarnet 34-37 cut-like homeobox 1 Mus musculus 4-7 2939095-12 1986 These observations suggest that PFA is an inhibitor of mammalian ribonucleotide reductase and that partial resistance to PFA can be effected by mutation to increased CDP reductase activity resulting in a large dCTP pool. Foscarnet 32-35 cut-like homeobox 1 Mus musculus 166-169 2939095-12 1986 These observations suggest that PFA is an inhibitor of mammalian ribonucleotide reductase and that partial resistance to PFA can be effected by mutation to increased CDP reductase activity resulting in a large dCTP pool. Foscarnet 121-124 cut-like homeobox 1 Mus musculus 166-169