PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
18768897-0	2008	4-1BB enhances proliferation of beryllium-specific T cells in the lung of subjects with chronic beryllium disease.	Beryllium	32-41	TNF receptor superfamily member 9	Homo sapiens	0-5	
18768897-0	2008	4-1BB enhances proliferation of beryllium-specific T cells in the lung of subjects with chronic beryllium disease.	Beryllium	96-105	TNF receptor superfamily member 9	Homo sapiens	0-5	
18768897-5	2008	Following beryllium exposure, CD4(+) T cells from blood and bronchoalveolar lavage of chronic beryllium disease patients up-regulate 4-1BB expression, and the majority of beryllium-responsive, IFN-gamma-producing CD4(+) T cells in blood coexpress CD28 and 4-1BB.	Beryllium	10-19	TNF receptor superfamily member 9	Homo sapiens	133-138	
18768897-5	2008	Following beryllium exposure, CD4(+) T cells from blood and bronchoalveolar lavage of chronic beryllium disease patients up-regulate 4-1BB expression, and the majority of beryllium-responsive, IFN-gamma-producing CD4(+) T cells in blood coexpress CD28 and 4-1BB.	Beryllium	10-19	TNF receptor superfamily member 9	Homo sapiens	256-261	
18768897-5	2008	Following beryllium exposure, CD4(+) T cells from blood and bronchoalveolar lavage of chronic beryllium disease patients up-regulate 4-1BB expression, and the majority of beryllium-responsive, IFN-gamma-producing CD4(+) T cells in blood coexpress CD28 and 4-1BB.	Beryllium	94-103	TNF receptor superfamily member 9	Homo sapiens	133-138	
18768897-5	2008	Following beryllium exposure, CD4(+) T cells from blood and bronchoalveolar lavage of chronic beryllium disease patients up-regulate 4-1BB expression, and the majority of beryllium-responsive, IFN-gamma-producing CD4(+) T cells in blood coexpress CD28 and 4-1BB.	Beryllium	94-103	TNF receptor superfamily member 9	Homo sapiens	256-261	
18768897-5	2008	Following beryllium exposure, CD4(+) T cells from blood and bronchoalveolar lavage of chronic beryllium disease patients up-regulate 4-1BB expression, and the majority of beryllium-responsive, IFN-gamma-producing CD4(+) T cells in blood coexpress CD28 and 4-1BB.	Beryllium	94-103	TNF receptor superfamily member 9	Homo sapiens	133-138	
18768897-5	2008	Following beryllium exposure, CD4(+) T cells from blood and bronchoalveolar lavage of chronic beryllium disease patients up-regulate 4-1BB expression, and the majority of beryllium-responsive, IFN-gamma-producing CD4(+) T cells in blood coexpress CD28 and 4-1BB.	Beryllium	94-103	TNF receptor superfamily member 9	Homo sapiens	256-261	
18768897-7	2008	In contrast to blood, inhibition of the 4-1BB ligand-4-1BB interaction partially blocked beryllium-induced proliferation of BAL CD4(+) T cells, and a lack of 4-1BB expression on BAL T cells was associated with increased beryllium-induced cell death.	Beryllium	89-98	TNF receptor superfamily member 9	Homo sapiens	40-45	
18768897-7	2008	In contrast to blood, inhibition of the 4-1BB ligand-4-1BB interaction partially blocked beryllium-induced proliferation of BAL CD4(+) T cells, and a lack of 4-1BB expression on BAL T cells was associated with increased beryllium-induced cell death.	Beryllium	89-98	TNF receptor superfamily member 9	Homo sapiens	53-58	
18768897-7	2008	In contrast to blood, inhibition of the 4-1BB ligand-4-1BB interaction partially blocked beryllium-induced proliferation of BAL CD4(+) T cells, and a lack of 4-1BB expression on BAL T cells was associated with increased beryllium-induced cell death.	Beryllium	89-98	TNF receptor superfamily member 9	Homo sapiens	53-58	
18768897-8	2008	Taken together, these findings suggest an important role of 4-1BB in the costimulation of beryllium-responsive CD4(+) T cells in the target organ.	Beryllium	90-99	TNF receptor superfamily member 9	Homo sapiens	60-65