PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 22450566-3 2012 The objective of the present work was to evaluate the impact of vanillin and ethyl vanillin on the activities of CYP2C9, CYP2E1, CYP3A4, CYP2B6 and CYP1A2 in human liver microsomes (HLM) in vitro, and impact on the activities of CYP1A2, CYP2C, CYP3A and CYP2E1 in rat liver microsomes (RLM) in vivo. ethyl vanillin 77-91 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 148-154 22450566-3 2012 The objective of the present work was to evaluate the impact of vanillin and ethyl vanillin on the activities of CYP2C9, CYP2E1, CYP3A4, CYP2B6 and CYP1A2 in human liver microsomes (HLM) in vitro, and impact on the activities of CYP1A2, CYP2C, CYP3A and CYP2E1 in rat liver microsomes (RLM) in vivo. ethyl vanillin 77-91 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 229-235 22450566-6 2012 The in vivo results revealed that drug interaction between vanillin/ethyl vanillin and the CYP2E1/CYP1A2-metabolizing drugs might be possible, and also suggested that the application of the above additives in foods and drugs should not be unlimited so as to avoid the adverse interaction. ethyl vanillin 68-82 cytochrome P450 family 1 subfamily A member 2 Homo sapiens 98-104