PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26689452-4 2016 To address these challenges, we have developed a new generation, Ca(II)-activated MRI contrast agent that utilizes ethyl esters to increase cell labeling and prevent extracellular divalent Ca(II) binding. ethyl esters 115-127 carbonic anhydrase 2 Homo sapiens 65-70 26689452-4 2016 To address these challenges, we have developed a new generation, Ca(II)-activated MRI contrast agent that utilizes ethyl esters to increase cell labeling and prevent extracellular divalent Ca(II) binding. ethyl esters 115-127 carbonic anhydrase 2 Homo sapiens 65-71 26689452-5 2016 Following labeling, the ethyl esters can be cleaved, thus allowing the agent to bind Ca(II), increasing relaxivity and resulting in enhanced positive MR image contrast. ethyl esters 24-36 carbonic anhydrase 2 Homo sapiens 85-91