PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 26839558-11 2016 The reduction of Akt-p at Ser-473 by NTG, DETA NONOate, and 8-Br-cGMP was significantly inhibited by ODQ, PKG-I. 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 42-54 AKT serine/threonine kinase 1 Homo sapiens 17-20 14500383-7 2003 We also observed a decline in the levels of cytosolic phospho-Akt at 16-24 h of DETA-NONOate treatment. 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 80-92 AKT serine/threonine kinase 1 Homo sapiens 62-65 24977346-6 2014 Incubation with DETA NONOate (a stable NO donor) and 8-Br-cGMP (a cell membrane permeable analog of cGMP) attenuated Akt phosphorylation at Ser-473, which was prevented by Rp-8-Br-PET-cGMPS (a specific inhibitor of PKG) and calyculin A (an inhibitor of protein phosphatase 1 and 2A) but not by okadaic acid (a selective inhibitor of protein phosphatase 2A). 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 16-28 AKT serine/threonine kinase 1 Homo sapiens 117-120 24977346-7 2014 Inhibition of Akt enhanced the relaxation and cGMP elevation of porcine pulmonary arteries induced by DETA NONOate or sodium nitroprusside, which was prevented by zaprinast, a specific inhibitor of PDE5. 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 102-114 AKT serine/threonine kinase 1 Homo sapiens 14-17 24518819-10 2014 Furthermore, DETANO stimulated Akt anti-apoptotic activity after 30 min in normoxia, whereas it inhibited Akt phosphorylation in hypoxia. 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 13-19 AKT serine/threonine kinase 1 Homo sapiens 31-34 24518819-10 2014 Furthermore, DETANO stimulated Akt anti-apoptotic activity after 30 min in normoxia, whereas it inhibited Akt phosphorylation in hypoxia. 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 13-19 AKT serine/threonine kinase 1 Homo sapiens 106-109 12763754-4 2003 Furthermore, ANG II also protected CFbs from apoptosis induced by the NO donor diethylenetriamine NONOate and this effect was associated with phosphorylation of Akt/protein kinase B at Ser473. 2,2'-(hydroxynitrosohydrazono)bis-ethanamine 79-105 AKT serine/threonine kinase 1 Homo sapiens 161-164