PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
20933602-11	2011	Hence, we have found that treatment of metastatic cancer cell lines with DETANONOate inhibited the EMT phenotype, through both the inhibition of the metastasis-inducers, NF-kappaB and Snail and the induction of the metastasis-suppressor, RKIP.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	73-84	phosphatidylethanolamine binding protein 1	Homo sapiens	238-242	
18477483-8	2008	In addition, DETANONOate induces the expression of the metastatic tumor suppressor gene product, Raf-1 Kinase Inhibitor Protein (RKIP), which inhibits the survival pathways induced by NF-kappaB and Raf-1/MEK which also contributes to the sensitizing activity.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	13-24	phosphatidylethanolamine binding protein 1	Homo sapiens	97-127	
21150329-7	2010	Further, treatment with DETANONOate inhibits Snail expression and DNA-binding activity in parallel with the upregulation of RKIP and E-cadherin protein levels.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	24-35	phosphatidylethanolamine binding protein 1	Homo sapiens	124-128	
21150329-8	2010	The pivotal roles of Snail inhibition and RKIP induction in DETANONOate-mediated inhibition of EMT were corroborated by both Snail silencing by siRNA and by ectopic expression of RKIP.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	60-71	phosphatidylethanolamine binding protein 1	Homo sapiens	42-46	
21150329-8	2010	The pivotal roles of Snail inhibition and RKIP induction in DETANONOate-mediated inhibition of EMT were corroborated by both Snail silencing by siRNA and by ectopic expression of RKIP.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	60-71	phosphatidylethanolamine binding protein 1	Homo sapiens	179-183	
18477483-10	2008	Inhibition of NF-kappaB activation by DETANONOate results downstream in the inhibition of the RKIP transcription repressor Snail, resulting in upregulation of RKIP.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	38-49	phosphatidylethanolamine binding protein 1	Homo sapiens	94-98	
18477483-10	2008	Inhibition of NF-kappaB activation by DETANONOate results downstream in the inhibition of the RKIP transcription repressor Snail, resulting in upregulation of RKIP.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	38-49	phosphatidylethanolamine binding protein 1	Homo sapiens	159-163	
18477483-8	2008	In addition, DETANONOate induces the expression of the metastatic tumor suppressor gene product, Raf-1 Kinase Inhibitor Protein (RKIP), which inhibits the survival pathways induced by NF-kappaB and Raf-1/MEK which also contributes to the sensitizing activity.	2,2'-(hydroxynitrosohydrazono)bis-ethanamine	13-24	phosphatidylethanolamine binding protein 1	Homo sapiens	129-133