PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 18586292-0 2008 Involvement of Bcl-xL degradation and mitochondrial-mediated apoptotic pathway in pyrrolizidine alkaloids-induced apoptosis in hepatocytes. Pyrrolizidine Alkaloids 82-105 BCL2-like 1 Mus musculus 15-21 18586292-10 2008 Meanwhile, another PA senecionine isolated from Senecio vulgaris L also induced apoptosis, caspase-3 activation and decreased Bcl-xL in mouse hepatocytes. Pyrrolizidine Alkaloids 19-21 BCL2-like 1 Mus musculus 126-132 18586292-11 2008 In conclusion, our results suggest that PAs may share the same hepatotoxic signal pathway, which involves degradation of Bcl-xL protein and thus leading to the activation of mitochondrial-mediated apoptotic pathway. Pyrrolizidine Alkaloids 40-43 BCL2-like 1 Mus musculus 121-127