PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
7515983-0	1994	Inhibitory effect of trimetazidine on thrombin-induced aggregation and calcium entry into human platelets.	Trimetazidine	21-34	coagulation factor II, thrombin	Homo sapiens	38-46	
7515983-3	1994	Preincubation with trimetazidine dose-dependently inhibited platelet aggregation induced by 0.05 U/ml thrombin (p < 0.001).	Trimetazidine	19-32	coagulation factor II, thrombin	Homo sapiens	102-110	
7515983-5	1994	In platelets stimulated by 0.05 U/ml thrombin, 0.1 mM trimetazidine did not modify pHi variations but decreased [Ca2+]i variations (p < 0.003, n = 16), blunting by 28 +/- 6% the transient peak of [Ca2+]i (p < 0.006) and decreasing by 6 +/- 2% the equilibrium value (p < 0.005).	Trimetazidine	54-67	coagulation factor II, thrombin	Homo sapiens	37-45	
7515983-7	1994	Trimetazidine therefore attenuates the Ca2+ influx evoked by thrombin, thereby limiting Ca2+ accumulation in stimulated platelets.	Trimetazidine	0-13	coagulation factor II, thrombin	Homo sapiens	61-69