PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 30233596-8 2018 Furthermore, using luciferase reporter gene and chromatin immunoprecipitation assays, we found that TMZ promoted the binding of the Nrf2 and CXCR2 promoter regions directly. Trimetazidine 100-103 chemokine (C-X-C motif) receptor 2 Mus musculus 141-146 30233596-9 2018 Application of CXCR2 inhibitor completely reversed the protective effects of TMZ in vivo. Trimetazidine 77-80 chemokine (C-X-C motif) receptor 2 Mus musculus 15-20 30233596-16 2018 What this study adds to our knowledge TMZ attenuated LPS-induced cardiomyocyte pyroptosis and cardiac dysfunction by promoting neutrophils recruitment to the heart tissues via CXCR2. Trimetazidine 38-41 chemokine (C-X-C motif) receptor 2 Mus musculus 176-181