PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 31604166-0 2019 Protective effects of naringin and trimetazidine on remote effect of acute renal injury on oxidative stress and myocardial injury through Nrf-2 regulation. Trimetazidine 35-48 NFE2 like bZIP transcription factor 2 Rattus norvegicus 138-143 31604166-2 2019 The aim of the current study was to examine the effects of naringin (NAR), trimetazidine (TMZ), or their combination on the Nrf-2 expression in the kidney tissue, and myocardial injury in the renal IR injury in rats. Trimetazidine 90-93 NFE2 like bZIP transcription factor 2 Rattus norvegicus 124-129 31604166-8 2019 CONCLUSION: NAR, TMZ, or their combination could attenuate the Nrf-2 expression in the kidney tissue, following the renal IR injury through inhibition of lipid peroxidase, and enhancement of antioxidant activity. Trimetazidine 17-20 NFE2 like bZIP transcription factor 2 Rattus norvegicus 63-68 31674935-6 2019 The combined use of TMZ and CoQ10 treatment was more effective than using either agent alone (p<0.01 for ROS, MDA, CAT, and cytosolic cyto-c; p<0.05 for SOD, nuclear Nrf2, and DeltaPsim loss). Trimetazidine 20-23 NFE2 like bZIP transcription factor 2 Rattus norvegicus 166-170 30890937-0 2019 Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-kappaB Signaling Pathway. Trimetazidine 0-13 NFE2 like bZIP transcription factor 2 Rattus norvegicus 101-105 30890937-8 2019 Furthermore, we found that TMZ suppressed oxidative stress and cardiomyocyte apoptosis via activation of Nrf2/HO-1 and inactivation of NF-kappaB signaling pathways. Trimetazidine 27-30 NFE2 like bZIP transcription factor 2 Rattus norvegicus 105-109