PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10343934-5	1999	The increase in IL-6 synthesis stimulates prostaglandin and leukotriene production causing dilatation of cervical vessels and further promoting the extravasation of leukocytes.	Leukotrienes	60-71	interleukin 6	Homo sapiens	16-20	
26597704-3	2016	In this study, we found that the low-affinity leukotriene B4 receptor-2 (BLT2) and its ligand leukotriene B4 were highly up-regulated in cisplatin-resistant SK-OV-3 ovarian cancer cells and play critical roles in mediating the chemoresistance through the activation of signal transducer and activator of transcription-3 (STAT-3) and the subsequent up-regulation of interleukin-6 (IL-6).	Leukotrienes	46-57	interleukin 6	Homo sapiens	365-378	
26597704-3	2016	In this study, we found that the low-affinity leukotriene B4 receptor-2 (BLT2) and its ligand leukotriene B4 were highly up-regulated in cisplatin-resistant SK-OV-3 ovarian cancer cells and play critical roles in mediating the chemoresistance through the activation of signal transducer and activator of transcription-3 (STAT-3) and the subsequent up-regulation of interleukin-6 (IL-6).	Leukotrienes	46-57	interleukin 6	Homo sapiens	380-384	
11859379-9	1996	Although IL-1-induced IL-6 expression was only affected when both prostaglandin and leukotriene biosynthesis were inhibited, elevated levels of PGE(2) but not leukotriene B(4), C(4), D(4), or E(4) were observed in the culture medium of IL-1-treated chondrocytes.	Leukotrienes	84-95	interleukin 6	Homo sapiens	22-26	
9329631-0	1997	Granulocyte-macrophage colony stimulating factor and interleukin-6 enhanced white blood cell synthesis of leukotrienes in chronic myelogenous leukemia.	Leukotrienes	106-118	interleukin 6	Homo sapiens	53-66	
9329631-1	1997	The effect of Granulocyte-Macrophage, Colony Stimulating Factor (GM-CSF) and Interleukin-6 (IL-6) on leukotriene production by CML white blood cells induced by calcium ionophore (A23187) was investigated and the leukotrienes formed were identified and quantified using high performance liquid chromatography (HPLC).	Leukotrienes	101-112	interleukin 6	Homo sapiens	77-90	
9329631-1	1997	The effect of Granulocyte-Macrophage, Colony Stimulating Factor (GM-CSF) and Interleukin-6 (IL-6) on leukotriene production by CML white blood cells induced by calcium ionophore (A23187) was investigated and the leukotrienes formed were identified and quantified using high performance liquid chromatography (HPLC).	Leukotrienes	101-112	interleukin 6	Homo sapiens	92-96	
9329631-3	1997	Although GM-CSF or IL-6 alone did not stimulate the synthesis of 5-lipoxygenase product, preincubation of the white blood cells of CML with GM-CSF or IL-6 for 30 minutes at 37 degrees C enhanced the ionophore A23187 induced leukotrienes synthesis, thus the CML white blood cell suspension primed with GM-CSF or IL-6 produced 26.6 +/- 2.8 and 18.9 +/- 1.3 pmol LTC4/10(6) cells respectively, and 30.2 +/- 3.6 and 25.5 +/- 2.5 Pmol LTB4/10(6) cells.	Leukotrienes	224-236	interleukin 6	Homo sapiens	150-154	
9329631-3	1997	Although GM-CSF or IL-6 alone did not stimulate the synthesis of 5-lipoxygenase product, preincubation of the white blood cells of CML with GM-CSF or IL-6 for 30 minutes at 37 degrees C enhanced the ionophore A23187 induced leukotrienes synthesis, thus the CML white blood cell suspension primed with GM-CSF or IL-6 produced 26.6 +/- 2.8 and 18.9 +/- 1.3 pmol LTC4/10(6) cells respectively, and 30.2 +/- 3.6 and 25.5 +/- 2.5 Pmol LTB4/10(6) cells.	Leukotrienes	224-236	interleukin 6	Homo sapiens	150-154	
1336653-0	1992	Interleukin 6 production by mononuclear phagocytes can be stimulated by leukotrienes.	Leukotrienes	72-84	interleukin 6	Homo sapiens	0-13	
1336653-7	1992	These data suggest that leukotrienes may modulate the production of IL6 and indicate some underlying mechanisms which may be involved.	Leukotrienes	24-36	interleukin 6	Homo sapiens	68-71