PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
12114539-6	2002	Among the members of the GADD family of genes, GADD153, GADD45 alpha, and GADD34 displayed marked, and GADD45 gamma showed minimal induction.	gadd	25-29	DNA damage inducible transcript 3	Homo sapiens	47-54	
18384088-7	2008	The growth arrest and DNA damage (GADD)-inducible transcription factor 153 (GADD153) mRNA and protein is markedly induced in a time- and concentration-dependent manner in response to 6-shogaol.	gadd	34-38	DNA damage inducible transcript 3	Homo sapiens	76-83	
10497233-8	1999	Nuclear run-on assays and mRNA decay studies suggested that the primary mechanism leading to increased GADD mRNA levels was not transcriptional, but rather that GADD45 and GADD153/CHOP expression were up-regulated in response to GLN deprivation via marked stabilization of these mRNAs.	gadd	103-107	DNA damage inducible transcript 3	Homo sapiens	180-184	
8168107-2	1994	Unlike GADD45, the response of other DNA damage-inducible genes to IR is not dependent on p53 based on the observation that induction in a panel of cell lines did not correlate with a normal p53 status; this included human GADD153, another member of the gadd (growth arrest and DNA damage inducible) group; MyD118, a gene related to GADD45; and the protooncogenes c-jun and c-fos.	gadd	254-258	DNA damage inducible transcript 3	Homo sapiens	223-230	
9413226-8	1997	Our conclusion is that GADD proteins play an important role in the malignant transformation of naevus to melanoma and GADD 45 and GADD 153 proteins can influence patient survival.	gadd	23-27	DNA damage inducible transcript 3	Homo sapiens	130-138	
8892753-3	1996	In contrast, the gadd gene stress response to base-damaging agents, such as methylmethane sulfonate (MMS) or UV radiation, or medium depletion (starvation) occurs in all mammalian cells examined to date regardless of p53 status for both GADD45 and also GADD153, which is not IR-responsive in many lines with functional p53.	gadd	17-21	DNA damage inducible transcript 3	Homo sapiens	253-260	
29227599-1	2016	We have studied hypoxic regulation of the expression of genes encoded GADD (growth arrest and DNAdamage) family proteins in U87 glioma cells in relation to inhibition of IRE1 (inositol requiring enzyme-1),which controls cell proliferation and tumor growth as a central mediator of endoplasmic reticulum stress.We have shown that hypoxia up-regulates the expression of GADD34, GADD45A, GADD45B, and GADD153genes, which are related to cell proliferation and apoptosis, in control (transfected by empty vector) gliomacells in gene specific manner.	gadd	70-74	DNA damage inducible transcript 3	Homo sapiens	398-405