PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 27117576-10 2016 We conclude that individuals with the variant allele may have lower TC and HDL-C levels due to increased activation of ANGPTL3 by ANGPTL8. Technetium 68-70 angiopoietin like 3 Homo sapiens 119-126 34417926-2 2022 Loss-of-function variants of the angiopoietin-like 3 (ANGPTL3) gene have been reported to be associated with several lipid-related CVD risk factors that include serum high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG) level, and total cholesterol (TC). Technetium 307-309 angiopoietin like 3 Homo sapiens 33-52 34417926-2 2022 Loss-of-function variants of the angiopoietin-like 3 (ANGPTL3) gene have been reported to be associated with several lipid-related CVD risk factors that include serum high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG) level, and total cholesterol (TC). Technetium 307-309 angiopoietin like 3 Homo sapiens 54-61 34422408-11 2021 The correlation between ANGPTL3 and either TC or LDL-C remained significant after adjusting for BMI. Technetium 43-45 angiopoietin like 3 Homo sapiens 24-31 28972399-2 2017 ANGPTL3 deficiency causes declined TG, total cholesterol (TC), LDL-C, high-density lipoprotein cholesterol (HDL-C), apolipoprotein B (apoB) and apolipoprotein A-I (apoA-I) serum concentration, a phenotype defined as familial combined hypolipidaemia (FHBL2). Technetium 58-60 angiopoietin like 3 Homo sapiens 0-7 28972399-9 2017 Subjects who carried ANGPTL3 sequence variants rs12563308 (n = 4) and rs199772471 (n = 1) had abnormally high TC and LDL-C concentrations. Technetium 110-112 angiopoietin like 3 Homo sapiens 21-28 28972399-12 2017 ANGPTL3 variant screen yielded five carriers with abnormally high TC concentration; the actual genetic causality, however, could not be verified. Technetium 66-68 angiopoietin like 3 Homo sapiens 0-7